Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
Resumen:
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.
| 2021 | |
|
Agencia Nacional de Investigación e Innovación FOCEM - Fondo para la Convergencia Estructural del Mercosur Ambassade de France à Montevideo |
|
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SARS-CoV-2 Testing strategies RT-PCR Antigenic test Ciencias Naturales y Exactas Ciencias Biológicas Virología |
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| Inglés | |
| Institut Pasteur de Montevideo | |
| IPMON en REDI | |
|
https://hdl.handle.net/20.500.12381/3466
https://doi.org/10.1016/j.coph.2021.12.006 |
|
| Acceso abierto | |
| Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. (CC BY-NC-ND) |
| _version_ | 1815413494701359104 |
|---|---|
| author | Fajardo, Álvaro |
| author2 | Perbolianachis, Paula Ferreiro, Irene Moreno, Pilar Moratorio, Gonzalo |
| author2_role | author author author author |
| author_facet | Fajardo, Álvaro Perbolianachis, Paula Ferreiro, Irene Moreno, Pilar Moratorio, Gonzalo |
| author_role | author |
| bitstream.checksum.fl_str_mv | 710ccfef5cb01d54b75d1d847d6b6b7b fc51672d42a22efd2d362cfdaa6a5536 |
| bitstream.checksumAlgorithm.fl_str_mv | MD5 MD5 |
| bitstream.url.fl_str_mv | https://redi.anii.org.uy/jspui/bitstream/20.500.12381/3466/2/license.txt https://redi.anii.org.uy/jspui/bitstream/20.500.12381/3466/1/1-s2.0-S1471489221001831-main.pdf |
| collection | IPMON en REDI |
| dc.creator.none.fl_str_mv | Fajardo, Álvaro Perbolianachis, Paula Ferreiro, Irene Moreno, Pilar Moratorio, Gonzalo |
| dc.date.accessioned.none.fl_str_mv | 2024-03-05T19:53:24Z |
| dc.date.available.none.fl_str_mv | 2024-03-05T19:53:24Z |
| dc.date.issued.none.fl_str_mv | 2021-12-21 |
| dc.description.abstract.none.fl_txt_mv | The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs. |
| dc.description.sponsorship.none.fl_txt_mv | Agencia Nacional de Investigación e Innovación FOCEM - Fondo para la Convergencia Estructural del Mercosur Ambassade de France à Montevideo |
| dc.format.extent.es.fl_str_mv | 152–158 |
| dc.identifier.anii.es.fl_str_mv | FCE_1_2019_1_156157 |
| dc.identifier.citation.es.fl_str_mv | Álvaro Fajardo, Paula Perbolianachis, Irene Ferreiro, Pilar Moreno, Gonzalo Moratorio, Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies, Current Opinion in Pharmacology, Volume 62, 2022, Pages 152-158, ISSN 1471-4892, https://doi.org/10.1016/j.coph.2021.12.006. |
| dc.identifier.doi.none.fl_str_mv | https://doi.org/10.1016/j.coph.2021.12.006 |
| dc.identifier.uri.none.fl_str_mv | https://hdl.handle.net/20.500.12381/3466 |
| dc.language.iso.none.fl_str_mv | eng |
| dc.publisher.es.fl_str_mv | Elsevier |
| dc.rights.*.fl_str_mv | Acceso abierto |
| dc.rights.license.none.fl_str_mv | Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. (CC BY-NC-ND) |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.es.fl_str_mv | Current Opinion in Pharmacology |
| dc.source.none.fl_str_mv | reponame:IPMON en REDI instname:Institut Pasteur de Montevideo instacron:Institut Pasteur de Montevideo |
| dc.subject.anii.none.fl_str_mv | Ciencias Naturales y Exactas Ciencias Biológicas Virología |
| dc.subject.es.fl_str_mv | SARS-CoV-2 Testing strategies RT-PCR Antigenic test |
| dc.title.none.fl_str_mv | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| dc.type.es.fl_str_mv | Artículo |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.version.es.fl_str_mv | Publicado |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | IPMON_fc4ebecc69e8c2d2ad850c4446c54c6e |
| identifier_str_mv | Álvaro Fajardo, Paula Perbolianachis, Irene Ferreiro, Pilar Moreno, Gonzalo Moratorio, Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies, Current Opinion in Pharmacology, Volume 62, 2022, Pages 152-158, ISSN 1471-4892, https://doi.org/10.1016/j.coph.2021.12.006. FCE_1_2019_1_156157 |
| instacron_str | Institut Pasteur de Montevideo |
| institution | Institut Pasteur de Montevideo |
| instname_str | Institut Pasteur de Montevideo |
| language | eng |
| network_acronym_str | IPMON |
| network_name_str | IPMON en REDI |
| oai_identifier_str | oai:redi.anii.org.uy:20.500.12381/3466 |
| publishDate | 2021 |
| reponame_str | IPMON en REDI |
| repository.mail.fl_str_mv | msarroca@pasteur.edu.uy |
| repository.name.fl_str_mv | IPMON en REDI - Institut Pasteur de Montevideo |
| repository_id_str | 9421_2 |
| rights_invalid_str_mv | Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. (CC BY-NC-ND) Acceso abierto |
| spelling | Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. (CC BY-NC-ND)Acceso abiertoinfo:eu-repo/semantics/openAccess2024-03-05T19:53:24Z2024-03-05T19:53:24Z2021-12-21Álvaro Fajardo, Paula Perbolianachis, Irene Ferreiro, Pilar Moreno, Gonzalo Moratorio, Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies, Current Opinion in Pharmacology, Volume 62, 2022, Pages 152-158, ISSN 1471-4892, https://doi.org/10.1016/j.coph.2021.12.006.https://hdl.handle.net/20.500.12381/3466FCE_1_2019_1_156157https://doi.org/10.1016/j.coph.2021.12.006The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.Agencia Nacional de Investigación e InnovaciónFOCEM - Fondo para la Convergencia Estructural del MercosurAmbassade de France à Montevideo152–158engElsevierCurrent Opinion in Pharmacologyreponame:IPMON en REDIinstname:Institut Pasteur de Montevideoinstacron:Institut Pasteur de MontevideoSARS-CoV-2Testing strategiesRT-PCRAntigenic testCiencias Naturales y ExactasCiencias BiológicasVirologíaMolecular accuracy vs antigenic speed: SARS-CoV-2 testing strategiesArtículoPublicadoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstitut Pasteur de MontevideoFacultad de Ciencias, Universidad de la República//Ciencias Naturales y Exactas/Ciencias Biológicas/VirologíaFajardo, ÁlvaroPerbolianachis, PaulaFerreiro, IreneMoreno, PilarMoratorio, GonzaloLICENSElicense.txtlicense.txttext/plain; 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en REDI - Institut Pasteur de Montevideofalse |
| spellingShingle | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies Fajardo, Álvaro SARS-CoV-2 Testing strategies RT-PCR Antigenic test Ciencias Naturales y Exactas Ciencias Biológicas Virología |
| status_str | publishedVersion |
| title | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| title_full | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| title_fullStr | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| title_full_unstemmed | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| title_short | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| title_sort | Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies |
| topic | SARS-CoV-2 Testing strategies RT-PCR Antigenic test Ciencias Naturales y Exactas Ciencias Biológicas Virología |
| url | https://hdl.handle.net/20.500.12381/3466 https://doi.org/10.1016/j.coph.2021.12.006 |
