Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies

Fajardo, Álvaro - Perbolianachis, Paula - Ferreiro, Irene - Moreno, Pilar - Moratorio, Gonzalo

Resumen:

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.


Detalles Bibliográficos
2021
Agencia Nacional de Investigación e Innovación
FOCEM - Fondo para la Convergencia Estructural del Mercosur
Ambassade de France à Montevideo
SARS-CoV-2
Testing strategies
RT-PCR
Antigenic test
Ciencias Naturales y Exactas
Ciencias Biológicas
Virología
Inglés
Institut Pasteur de Montevideo
IPMON en REDI
https://hdl.handle.net/20.500.12381/3466
https://doi.org/10.1016/j.coph.2021.12.006
Acceso abierto
Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. (CC BY-NC-ND)