Zygote cryobanking applied to CRISPR/Cas9 microinjection in mice. (Research article).
Resumen:
ABSTRACT.- Microinjection of CRISPR/Cas9 requires the availability of zygotes that implies animal breeding, superovulation schemes, and embryo collection. Vitrification of zygotes may allow having ready-to-use embryos and to temporally dissociate the workload of embryo production from microinjection. In this study, fresh (F group) or vitrified (V group) zygotes were microinjected with CRISPR/Cas9 system to test the hypothesis that vitrified zygotes could be a suitable source of embryos for microinjection. @ Schlapp et al.
| 2024 | |
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ANIMALS CRYOPRESERVATION PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA Mutation rate Embryo Transfer Microinjection Fertility Preservation CRISPR/Cas9 CRISPR-CAS9 system |
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| Inglés | |
| Instituto Nacional de Investigación Agropecuaria | |
| AINFO | |
| https://ainfo.inia.uy/consulta/busca?b=pc&id=64858&biblioteca=vazio&busca=64858&qFacets=64858 | |
| Acceso abierto |
