E-Cadherin gene expression in oral cancer : Clinical and prospective data
Resumen:
Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics.
| 2019 | |
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Oral cancer E-Cadherin Gene expression |
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| Inglés | |
| Universidad de la República | |
| COLIBRI | |
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https://hdl.handle.net/20.500.12008/25951
https://doi.org/10.4317/medoral.23029 |
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| Acceso abierto | |
| Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| _version_ | 1807522952589082624 |
|---|---|
| author | López-Verdín, Sandra |
| author2 | de la Luz Martínez-Fierro, Margarita Garza-Veloz, Idalia Zamora Pérez, Ana Lourdes Grajeda-Cruz, Jonathan González-González, Rogelio Molina-Frechero, Nelly Arocena, Miguel Bologna-Molina, Ronell |
| author2_role | author author author author author author author author |
| author_facet | López-Verdín, Sandra de la Luz Martínez-Fierro, Margarita Garza-Veloz, Idalia Zamora Pérez, Ana Lourdes Grajeda-Cruz, Jonathan González-González, Rogelio Molina-Frechero, Nelly Arocena, Miguel Bologna-Molina, Ronell |
| author_role | author |
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| collection | COLIBRI |
| dc.contributor.filiacion.none.fl_str_mv | López-Verdín Sandra de la Luz Martínez-Fierro Margarita Garza-Veloz Idalia Zamora Pérez Ana Lourdes Grajeda-Cruz Jonathan González-González Rogelio Molina-Frechero Nelly Arocena Miguel, Universidad de la República (Uruguay). Facultad de Odontología Bologna-Molina Ronell, Universidad de la República (Uruguay). Facultad de Odontología |
| dc.creator.none.fl_str_mv | López-Verdín, Sandra de la Luz Martínez-Fierro, Margarita Garza-Veloz, Idalia Zamora Pérez, Ana Lourdes Grajeda-Cruz, Jonathan González-González, Rogelio Molina-Frechero, Nelly Arocena, Miguel Bologna-Molina, Ronell |
| dc.date.accessioned.none.fl_str_mv | 2020-11-25T13:54:46Z |
| dc.date.available.none.fl_str_mv | 2020-11-25T13:54:46Z |
| dc.date.issued.none.fl_str_mv | 2019 |
| dc.description.abstract.none.fl_txt_mv | Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics. |
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| dc.identifier.citation.es.fl_str_mv | López-Verdín, S, de la Luz Martínez-Fierro, M, Garza-Veloz, I, y otros. "E-Cadherin gene expression in oral cancer : Clinical and prospective data". Medicina Oral. [en línea] Patología oral y Cirugía Bucal, 24(4), e444–e451, 2019 .https://doi.org/10.4317/medoral.23029 |
| dc.identifier.doi.none.fl_str_mv | https://doi.org/10.4317/medoral.23029 |
| dc.identifier.issn.none.fl_str_mv | 1698-6946 |
| dc.identifier.uri.none.fl_str_mv | https://hdl.handle.net/20.500.12008/25951 |
| dc.language.iso.none.fl_str_mv | en eng |
| dc.relation.ispartof.es.fl_str_mv | Medicina Oral, Patología oral y Cirugía Bucal, 24(4), e444–e451, 2019 |
| dc.rights.license.none.fl_str_mv | Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.es.fl_str_mv | Oral cancer E-Cadherin Gene expression |
| dc.title.none.fl_str_mv | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| dc.type.es.fl_str_mv | Artículo |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | COLIBRI_ecda90ce2e992d6ab64ada661feb7992 |
| identifier_str_mv | López-Verdín, S, de la Luz Martínez-Fierro, M, Garza-Veloz, I, y otros. "E-Cadherin gene expression in oral cancer : Clinical and prospective data". Medicina Oral. [en línea] Patología oral y Cirugía Bucal, 24(4), e444–e451, 2019 .https://doi.org/10.4317/medoral.23029 1698-6946 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | COLIBRI |
| network_name_str | COLIBRI |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/25951 |
| publishDate | 2019 |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | mabel.seroubian@seciu.edu.uy |
| repository.name.fl_str_mv | COLIBRI - Universidad de la República |
| repository_id_str | 4771 |
| rights_invalid_str_mv | Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| spelling | López-Verdín Sandrade la Luz Martínez-Fierro MargaritaGarza-Veloz IdaliaZamora Pérez Ana LourdesGrajeda-Cruz JonathanGonzález-González RogelioMolina-Frechero NellyArocena Miguel, Universidad de la República (Uruguay). Facultad de OdontologíaBologna-Molina Ronell, Universidad de la República (Uruguay). Facultad de Odontología2020-11-25T13:54:46Z2020-11-25T13:54:46Z2019López-Verdín, S, de la Luz Martínez-Fierro, M, Garza-Veloz, I, y otros. "E-Cadherin gene expression in oral cancer : Clinical and prospective data". Medicina Oral. [en línea] Patología oral y Cirugía Bucal, 24(4), e444–e451, 2019 .https://doi.org/10.4317/medoral.230291698-6946https://hdl.handle.net/20.500.12008/25951https://doi.org/10.4317/medoral.23029Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics.Submitted by Luna Fabiana (fabiana.luna@fic.edu.uy) on 2020-11-25T13:54:04Z No. of bitstreams: 2 license_rdf: 21687 bytes, checksum: 749156fd3854beb422ddf543c77fb5b1 (MD5) E Cadherin gene 2019.pdf: 1207026 bytes, checksum: 7fb03f2e464b42dadaef98211f5e4af4 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@fic.edu.uy) on 2020-11-25T13:54:46Z (GMT). No. of bitstreams: 2 license_rdf: 21687 bytes, checksum: 749156fd3854beb422ddf543c77fb5b1 (MD5) E Cadherin gene 2019.pdf: 1207026 bytes, checksum: 7fb03f2e464b42dadaef98211f5e4af4 (MD5) Previous issue date: 2019application/pdfenengMedicina Oral, Patología oral y Cirugía Bucal, 24(4), e444–e451, 2019Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)Oral cancerE-CadherinGene expressionE-Cadherin gene expression in oral cancer : Clinical and prospective dataArtículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaLópez-Verdín, Sandrade la Luz Martínez-Fierro, MargaritaGarza-Veloz, IdaliaZamora Pérez, Ana LourdesGrajeda-Cruz, JonathanGonzález-González, RogelioMolina-Frechero, NellyArocena, MiguelBologna-Molina, RonellLICENSElicense.txtlicense.txttext/plain; charset=utf-84267http://localhost:8080/xmlui/bitstream/20.500.12008/25951/5/license.txt6429389a7df7277b72b7924fdc7d47a9MD55LICENSElicense.txtlicense.txttext/plain; charset=utf-84267http://localhost:8080/xmlui/bitstream/20.500.12008/25951/6/license.txt6429389a7df7277b72b7924fdc7d47a9MD56CC-LICENSElicense_urllicense_urltext/plain; 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- Universidad de la Repúblicafalse |
| spellingShingle | E-Cadherin gene expression in oral cancer : Clinical and prospective data López-Verdín, Sandra Oral cancer E-Cadherin Gene expression |
| status_str | publishedVersion |
| title | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| title_full | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| title_fullStr | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| title_full_unstemmed | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| title_short | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| title_sort | E-Cadherin gene expression in oral cancer : Clinical and prospective data |
| topic | Oral cancer E-Cadherin Gene expression |
| url | https://hdl.handle.net/20.500.12008/25951 https://doi.org/10.4317/medoral.23029 |
