E-Cadherin gene expression in oral cancer : Clinical and prospective data

López-Verdín, Sandra - de la Luz Martínez-Fierro, Margarita - Garza-Veloz, Idalia - Zamora Pérez, Ana Lourdes - Grajeda-Cruz, Jonathan - González-González, Rogelio - Molina-Frechero, Nelly - Arocena, Miguel - Bologna-Molina, Ronell

Resumen:

Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics.


Detalles Bibliográficos
2019
Oral cancer
E-Cadherin
Gene expression
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/25951
https://doi.org/10.4317/medoral.23029
Acceso abierto
Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)