E-Cadherin gene expression in oral cancer : Clinical and prospective data
Resumen:
Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics.
| 2019 | |
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Oral cancer E-Cadherin Gene expression |
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| Inglés | |
| Universidad de la República | |
| COLIBRI | |
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https://hdl.handle.net/20.500.12008/25951
https://doi.org/10.4317/medoral.23029 |
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| Acceso abierto | |
| Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| Sumario: | Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics. |
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