Arterial pulse pressure amplification described by means of a nonlinear wave model : Characterization of human aging

Alfonso, Manuel Roberto - Cymberknop, Leandro Javier - Armentano, Ricardo L - Pessana, Franco - Wray, Sandra - Legnani, Walter Edgardo

Resumen:

The representation of blood pressure pulse as a combination of solitons captures many of the phenomena observed during its propagation along the systemic circulation. The aim of this work is to analyze the applicability of a compartmental model for propagation regarding the pressure pulse amplification associated with arterial aging. The model was applied to blood pressure waveforms that were synthesized using solitons, and then validated by waveforms obtained from individuals from differentiated age groups. Morphological changes were verified in the blood pressure waveform as a consequence of the aging process (i.e. due to the increase in arterial stiffness). These changes are the result of both a nonlinear interaction and the phenomena present in the propagation of nonlinear mechanic waves.


Detalles Bibliográficos
2016
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/42702
Acceso abierto
Licencia Creative Commons Atribución (CC - By 4.0)