Integrative analysis of nuclear biomechanics by AI-enhanced quantitative phase microscopy in CAL27 oral carcinoma cells.
Resumen:
The dynamics of the cell nucleus relect important aspects of the internal organization and the pathophysiological state of cells. In this work, we built an artificial intelligence-enhanced approach for the quantitative analysis of nuclear rotation in CAL27 oral carcinoma cells cultured under different experimental conditions. Using label-free quantitative phase microscopy, we performed a time-lapse tracking of individual nuclei to compare rotational dynamics under stimuli such as hypoxia, chemotherapy (cisplatin treatment), and rotenone.
| 2025 | |
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Oral carcinoma cells CAL27 Artificial intelligence |
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| Inglés | |
| Universidad de la República | |
| COLIBRI | |
| https://hdl.handle.net/20.500.12008/53488 | |
| Acceso abierto | |
| Licencia Creative Commons Atribución (CC - By 4.0) |
