Mitochondrial morphology in fertile and infertile men : Image processing and morphometric analysis of the sperm midpiece
Resumen:
The male factor is responsible for 50% of infertility cases. Numerous studies have explored the relationship between human sperm morphology assessed via optical and electron microscopy and reproductive outcomes. In the sperm midpiece, mitochondria are arranged in a helical shape, forming a compact sheath. Disruptions in this precise mitochondrial structure, size, or organization may contribute to infertility. However, despite established links between abnormal sperm morphology and pathology, mitochondrial abnormalities in sperm remain relatively understudied.
| 2025 | |
|
Comisión Sectorial de Investigación Científica (CSIC I+D 2016, ID23), Universidad de la República(UdelaR) UdelaR Espacio Interdisciplinario, Núcleos 2015, UdelaR Programa de Desarrollo de las Ciencias Básicas (PEDECIBA) Iniciativa Chan Zuckerberg que amplía el acceso global a la bioimagen |
|
|
Human infertility Sperm midpiece Sperm mitochondria Fluorescent probes Electron microscopy Image processing |
|
| Inglés | |
| Universidad de la República | |
| COLIBRI | |
|
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2025.1609081/full
https://hdl.handle.net/20.500.12008/52729 |
|
| Acceso abierto | |
| Licencia Creative Commons Atribución (CC - By 4.0) |
