Proteoglycans as potential biomarkers in odontogenic tumors

Gómez Herrera, Z. - Molina Frechero, Nelly - Damian Matsumura, P. - Bologna-Molina, Ronell

Resumen:

Proteoglycans (PGs) are essential for normal cellular development; however, alterations of their concentrations can promote tumor growth. To date, a limited number of studies report the presence of PGs in odontogenic tumors (OTs); therefore, the main purpose of this work is to gather the information published on the study of PGs. The search reported 26 articles referring to the presence of different PGs in distinct OTs from 1999 to May 2017. PGs seem to play an important role during OTs’ development as they are involved in several tumor processes; however, the number of reports on the study of these molecules is low. Thus, more studies are necessary in order to gain a better understanding of the underlying pathophysiology of OTs.


Detalles Bibliográficos
2018
Biglycan
CD44
Glypican
Odontogenic tumor
Proteoglycan
Syndecan
Versican
Perlecan
Tumor odontogénico
Inglés
Universidad de la República
COLIBRI
http://hdl.handle.net/20.500.12008/18470
Acceso abierto

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