Proteoglycans as potential biomarkers in odontogenic tumors

 

Autor(es):
Gómez Herrera, Z. ; Molina Frechero, Nelly ; Damian Matsumura, P. ; Bologna Molina, Ronell
Tipo:
Artículo
Versión:
Publicado
Resumen:

Proteoglycans (PGs) are essential for normal cellular development; however, alterations of their concentrations can promote tumor growth. To date, a limited number of studies report the presence of PGs in odontogenic tumors (OTs); therefore, the main purpose of this work is to gather the information published on the study of PGs. The search reported 26 articles referring to the presence of different PGs in distinct OTs from 1999 to May 2017. PGs seem to play an important role during OTs’ development as they are involved in several tumor processes; however, the number of reports on the study of these molecules is low. Thus, more studies are necessary in order to gain a better understanding of the underlying pathophysiology of OTs.

Año:
2018
Idioma:
Inglés
Temas:
Biglycan
CD44
Glypican
Odontogenic tumor
Proteoglycan
Syndecan
Versican
Perlecan
Tumor odontogénico
Institución:
Universidad de la República
Repositorio:
COLIBRI
Enlace(s):
http://hdl.handle.net/20.500.12008/18470
Nivel de acceso:
Acceso abierto