Few cases of nontraumatic rupture of the spleen in diffuse B-cell lymphoma have been reported.   We present a case of a 73-year-old man, multiple comorbidities that hours before biopsy puncture of the liver nodule installed abdominal pain and hypovolemic shock. An emergency operation was performed. A pathological spleen was found with a ruptured nodule, bleeding and moderate hemoperitoneum. Splenectomy was performed. At 96 hours, he installed abdominal pain and shock. The liver node and hemoperitoneum rupture and bleeding, hemodynamic instability and intraoperative death were reoperated and confirmed. The pathological anatomic study diagnosed diffuse large B-cell lymphoma.

Pocos casos se han comunicado de rotura no traumática de bazo en linfoma difuso de células B. Se presenta un caso de un hombre de 73 años, múltiples comorbilidades que horas previas a punción biópsica de nódulo hepático instaló dolor abdominal y shock hipovolémico. Se operó de emergencia. Se constató bazo patológico con nódulo roto, sangrando y hemoperitoneo moderado. Se realizó la esplenectomía. A las 96 horas instaló dolor abdominal y shock. Se reoperó y constató rotura y sangrado de nódulo hepático y hemoperitoneo, inestabilidad hemodinámica y muerte intraoperatoria. El estudio anátomo patológico diagnosticó linfoma difuso de células B grandes.