Massive pulmonary tumor microembolism secondary to hepatic dearterialization due to embolization of a hepatocarcinoma
Microembolismo tumoral pulmonar masivo secundario a desarterialización hepática por embolización de un hepatocarcinoma
Resumen:
A 59 - year - old male patient develo"ped massive tumora microembolism secondary to hepatic dearterialization resulting from selective arterial embolization of a hepatocarcinoma. He entered the hospital as a result of pain in right hemi - thorax, hepatomegalia and general repercussion. Paraclinicar studies ( hepatic scintollography, arteriography, laparoscopy and biopsy) indicated a multinodular hepatocarcinoma. Hepatic dearterialization for antalgic purposes was decided. The procedure was followed by the clinical picture which is typical of multiple pulmonary embolism. Death occurred 30 hours after surgery. Post mortem showed a differentiated multinodular hepato'carcinoma, partially necrosed, which had developed in a cyrrhotic liver with intrasinusoidal hepatic metastasis. Multiple tumoral microembolism had occurred in both lungs, The cause of death was attributed to release of tumoral emboli originated in necrosis of neoplasic growths in the interior of suprahepatic veins. The paper contemplates the possibility that intrasinusoidal hepatic metastases are secondary to tumoral emboli released inthe portal venous system; these might also condition a portal thrombosis. Study of this case leads to the conclusio'n that an exhaustive evaluation of the portal venous and suprahepatic systems should be performed in cases hepaticdearterialization due to hepatocarcinoma.
Presentación de un caso de microembolismo tumoral mas,ivo secundario a la desarterialización hepática por embolización arterial selectiva de un hepatocarcinoma.Se trataba de un hombre de 59 años que ingresó por dolor en hemitórax derecho, hepatom, egalia y repercusión general. Los estudios paraclínicos (centellografía hepática, arteriografía, laparoscopía y biopsia) demostraron que se trataba de un hepatocarcinoma multinodular. Se decidió realizar la desarterialización hepática con fines antálgicos. El procedimiento fue seguido de un cuadro clínico típico de embolismo pulmonar múltiple. La muerte se produjo alas 30 hrs. del procedimiento. La autopsia demostró un hepafucarcinoma multinodular diferenciado, parcialmente necrosado, desarrollado en un hígado cirrótico con metástasis hepáticas intrasinusoidales. En ambos pulmones se comprobó microemboUsmo tumoral múltiple.La causa de muerte se atribuye al desprendimientode émbolos tumorales originados en la necrosis de brotes neoplásicos que crecen en el interior de las venas suprahepáticas. Se plantea la posibilidad de que las metástasis intrasinusoidales hepáticas sean secundarias a émbolos tumorales; desprendidos en el sistema venosoportal, que incluso podrían condicionar una trombosis portal.A propósito del caso se enfatiza en la necesidad de una evaluación exhaustiva de los sistemas venosos portal y suprahepático cuando se plantea efectuar una desart'erialización hepática en un hepatocarcinoma.
1979 | |
embolización terapéutica embolization therapeutic |
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Español | |
Sociedad de Cirugía del Uruguay | |
Revista Cirugía del Uruguay | |
https://revista.scu.org.uy/index.php/cir_urug/article/view/3123 | |
Acceso abierto |
Sumario: | A 59 - year - old male patient develo"ped massive tumora microembolism secondary to hepatic dearterialization resulting from selective arterial embolization of a hepatocarcinoma. He entered the hospital as a result of pain in right hemi - thorax, hepatomegalia and general repercussion. Paraclinicar studies ( hepatic scintollography, arteriography, laparoscopy and biopsy) indicated a multinodular hepatocarcinoma. Hepatic dearterialization for antalgic purposes was decided. The procedure was followed by the clinical picture which is typical of multiple pulmonary embolism. Death occurred 30 hours after surgery. Post mortem showed a differentiated multinodular hepato'carcinoma, partially necrosed, which had developed in a cyrrhotic liver with intrasinusoidal hepatic metastasis. Multiple tumoral microembolism had occurred in both lungs, The cause of death was attributed to release of tumoral emboli originated in necrosis of neoplasic growths in the interior of suprahepatic veins. The paper contemplates the possibility that intrasinusoidal hepatic metastases are secondary to tumoral emboli released inthe portal venous system; these might also condition a portal thrombosis. Study of this case leads to the conclusio'n that an exhaustive evaluation of the portal venous and suprahepatic systems should be performed in cases hepaticdearterialization due to hepatocarcinoma. |
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