Infusion chemotherapy in malignant melanoma
Quimioterapia por perfusión en el melanoma maligno
Resumen:
A description is given of the perfusion method with Phenyl-Alanine-Mustard, in the treatment of malignant melanomas of the extremities. An analysis was made of the results obtained in 20 cases treated. Attention was called to the anatómopathological modifications which were observed, such as, reduction in the size of tt¡mor, necrosis of same, cell lysis, liberation of melanotic pigments, etc. 'I'he e:f'fect of the drug appears to be more significant in pigmented than in amelanotic tumors. In no case was total disappearance of the tumor achieved and, consequently, this method is considered as complementaryto surgery.
Se describe el método de la perfusión en el miembro aislado con la Fenil-Alanina-Mostaza en el tratamiento de los melanomas malignos de los miembros,analizándose los resultados obtenidos en 20 procedimientos realizados. Destacamos las modificaciones anatomopatológicas observadas, tales como: disminución en el tamaño deltumor, necrosis del mismo, lisis celulares, liberación d<c pigmentos melánicos, etc. La acción de la droga parece ser mayor en los tumores pigmentados que enlo
1974 | |
melanoma quimioterapia melanoma chemotherapy |
|
Español | |
Sociedad de Cirugía del Uruguay | |
Revista Cirugía del Uruguay | |
https://revista.scu.org.uy/index.php/cir_urug/article/view/2682 | |
Acceso abierto |
_version_ | 1815772763135148032 |
---|---|
author | Priario, Julio C |
author_facet | Priario, Julio C |
author_role | author |
collection | Revista Cirugía del Uruguay |
dc.creator.none.fl_str_mv | Priario, Julio C |
dc.date.none.fl_str_mv | 1974-02-25 |
dc.description.abstract.none.fl_txt_mv | A description is given of the perfusion method with Phenyl-Alanine-Mustard, in the treatment of malignant melanomas of the extremities. An analysis was made of the results obtained in 20 cases treated. Attention was called to the anatómopathological modifications which were observed, such as, reduction in the size of tt¡mor, necrosis of same, cell lysis, liberation of melanotic pigments, etc. 'I'he e:f'fect of the drug appears to be more significant in pigmented than in amelanotic tumors. In no case was total disappearance of the tumor achieved and, consequently, this method is considered as complementaryto surgery. Se describe el método de la perfusión en el miembro aislado con la Fenil-Alanina-Mostaza en el tratamiento de los melanomas malignos de los miembros,analizándose los resultados obtenidos en 20 procedimientos realizados. Destacamos las modificaciones anatomopatológicas observadas, tales como: disminución en el tamaño deltumor, necrosis del mismo, lisis celulares, liberación d<c pigmentos melánicos, etc. La acción de la droga parece ser mayor en los tumores pigmentados que enlo |
dc.format.none.fl_str_mv | application/pdf |
dc.identifier.none.fl_str_mv | https://revista.scu.org.uy/index.php/cir_urug/article/view/2682 |
dc.language.iso.none.fl_str_mv | spa |
dc.publisher.none.fl_str_mv | Sociedad de Cirugía del Uruguay |
dc.relation.none.fl_str_mv | https://revista.scu.org.uy/index.php/cir_urug/article/view/2682/2576 |
dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
dc.source.none.fl_str_mv | Revista Cirugía del Uruguay; Vol. 44 No. 5 (1974): Cirugía del Uruguay; 384-387 Revista Cirugía del Uruguay; Vol. 44 Núm. 5 (1974): Cirugía del Uruguay; 384-387 1688-1281 reponame:Revista Cirugía del Uruguay instname:Sociedad de Cirugía del Uruguay instacron:Sociedad de Cirugía del Uruguay |
dc.subject.none.fl_str_mv | melanoma quimioterapia melanoma chemotherapy |
dc.title.none.fl_str_mv | Infusion chemotherapy in malignant melanoma Quimioterapia por perfusión en el melanoma maligno |
dc.type.none.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
description | A description is given of the perfusion method with Phenyl-Alanine-Mustard, in the treatment of malignant melanomas of the extremities. An analysis was made of the results obtained in 20 cases treated. Attention was called to the anatómopathological modifications which were observed, such as, reduction in the size of tt¡mor, necrosis of same, cell lysis, liberation of melanotic pigments, etc. 'I'he e:f'fect of the drug appears to be more significant in pigmented than in amelanotic tumors. In no case was total disappearance of the tumor achieved and, consequently, this method is considered as complementaryto surgery. |
eu_rights_str_mv | openAccess |
format | article |
id | SCU_1_a82fac8d7fe643076c0d1f07352d265b |
instacron_str | Sociedad de Cirugía del Uruguay |
institution | Sociedad de Cirugía del Uruguay |
instname_str | Sociedad de Cirugía del Uruguay |
language | spa |
network_acronym_str | SCU_1 |
network_name_str | Revista Cirugía del Uruguay |
oai_identifier_str | oai:ojs2.revista.scu.org.uy:article/2682 |
publishDate | 1974 |
publisher.none.fl_str_mv | Sociedad de Cirugía del Uruguay |
reponame_str | Revista Cirugía del Uruguay |
repository.mail.fl_str_mv | |
repository.name.fl_str_mv | Revista Cirugía del Uruguay - Sociedad de Cirugía del Uruguay |
repository_id_str | |
spelling | Infusion chemotherapy in malignant melanomaQuimioterapia por perfusión en el melanoma malignoPriario, Julio CmelanomaquimioterapiamelanomachemotherapyA description is given of the perfusion method with Phenyl-Alanine-Mustard, in the treatment of malignant melanomas of the extremities. An analysis was made of the results obtained in 20 cases treated. Attention was called to the anatómopathological modifications which were observed, such as, reduction in the size of tt¡mor, necrosis of same, cell lysis, liberation of melanotic pigments, etc. 'I'he e:f'fect of the drug appears to be more significant in pigmented than in amelanotic tumors. In no case was total disappearance of the tumor achieved and, consequently, this method is considered as complementaryto surgery.Se describe el método de la perfusión en el miembro aislado con la Fenil-Alanina-Mostaza en el tratamiento de los melanomas malignos de los miembros,analizándose los resultados obtenidos en 20 procedimientos realizados. Destacamos las modificaciones anatomopatológicas observadas, tales como: disminución en el tamaño deltumor, necrosis del mismo, lisis celulares, liberación d<c pigmentos melánicos, etc. La acción de la droga parece ser mayor en los tumores pigmentados que enloSociedad de Cirugía del Uruguay1974-02-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revista.scu.org.uy/index.php/cir_urug/article/view/2682Revista Cirugía del Uruguay; Vol. 44 No. 5 (1974): Cirugía del Uruguay; 384-387Revista Cirugía del Uruguay; Vol. 44 Núm. 5 (1974): Cirugía del Uruguay; 384-3871688-1281reponame:Revista Cirugía del Uruguayinstname:Sociedad de Cirugía del Uruguayinstacron:Sociedad de Cirugía del Uruguayspahttps://revista.scu.org.uy/index.php/cir_urug/article/view/2682/2576info:eu-repo/semantics/openAccess2021-02-25T21:27:40Zoai:ojs2.revista.scu.org.uy:article/2682Privadahttps://scu.org.uy/https://revista.scu.org.uy/index.php/cir_urug/oaiUruguayopendoar:2021-02-25T21:27:40Revista Cirugía del Uruguay - Sociedad de Cirugía del Uruguayfalse |
spellingShingle | Infusion chemotherapy in malignant melanoma Priario, Julio C melanoma quimioterapia melanoma chemotherapy |
status_str | publishedVersion |
title | Infusion chemotherapy in malignant melanoma |
title_full | Infusion chemotherapy in malignant melanoma |
title_fullStr | Infusion chemotherapy in malignant melanoma |
title_full_unstemmed | Infusion chemotherapy in malignant melanoma |
title_short | Infusion chemotherapy in malignant melanoma |
title_sort | Infusion chemotherapy in malignant melanoma |
topic | melanoma quimioterapia melanoma chemotherapy |
url | https://revista.scu.org.uy/index.php/cir_urug/article/view/2682 |