Local norepinephrine value in the control of bleeding by acute gastric ulcers
Valor de la noradrenalina local en el control de las hemorragias por úlceras gástricas agudas
Resumen:
An experimental model of acute gastric ulcer was reproduced in 24 dogs, according to the procedure: deviced by Le Veen. Animals were grouped into 3 equal series of 8 dogs each. One of the series was used as control and the other 2 were treated with a norepinephrine solution ( at different concentrations and during different times) in a topic, endogastric -way in an attempt to arrest the bleeding. lt was proved that, at a 16 mg/lt concentration, the drug gives a number of survivors which is higher than that of the non-treated animals, without undersirable side-effects.
En 24 perros se reproduce un m.odelo experimen tal de úlceras gástricas agudas, según procedimiento ideado por LeVeen. Se dividen los animales en 3 series iguales de ocho. Una se deja como testigo y a las 2 restantes se les trata con solución de noradrenalina (a concentraciones y durante tiempos diferentes) en forma tópica, endogástrica, para intentar cohibir el sangrado. Se comprueba que a una concentración de 16 mg/lt, la droga condiciona un mayor número de sobrevivientes que en los animales no tratados, sin efectos colaterales indeseables.
1975 | |
hemorragia gastrointestinal terapia úlcera estomacal norepinefrina uso uso terapéutico hemorrhage gastrointestinal therapy stomach ulcer norepinephrine therapeutic use |
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Español | |
Sociedad de Cirugía del Uruguay | |
Revista Cirugía del Uruguay | |
https://revista.scu.org.uy/index.php/cir_urug/article/view/2695 | |
Acceso abierto |
Sumario: | An experimental model of acute gastric ulcer was reproduced in 24 dogs, according to the procedure: deviced by Le Veen. Animals were grouped into 3 equal series of 8 dogs each. One of the series was used as control and the other 2 were treated with a norepinephrine solution ( at different concentrations and during different times) in a topic, endogastric -way in an attempt to arrest the bleeding. lt was proved that, at a 16 mg/lt concentration, the drug gives a number of survivors which is higher than that of the non-treated animals, without undersirable side-effects. |
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