Combined radiation therapy and surgery in the treatment of esophageal cancer

Radioterapia y cirugía combinadas en el tratamiento del cáncer de esófago

Praderi, Luis A - Parada, Ricardo

Resumen:

The authors suggest a eombined treatmcnt of preoperative irradiation and surgical excision for patients with careinoma of tbe esophagus. Wlth cobalt-60 gammo. rays thy give a dose of 4000 rads jn 3 weeks, in a large fieId, 8 cm wide and 15 cm or more high, centered by the lesiono They do not carry out a total irradiation oí the esophagus, nOr oí tbe celiac regian. 2 wceks aíter discontinuing radiotherapy, they perform the eso· phagectorny with proximal gastrectomy and celiae Iymph nodes excision by a single left thoraeic approach for juxtufreoie tumors, and by a combined approaCh, abdo· minal and right thoracie, for the tumors of the ntlddlc third or the uppcr ones of the lower third. In all cases continulty was restored by intrathoracic esophago-gastrostomy. Out oi. the 18 p;\tients thus treated 16 were res~cted (88 % ). Operative mortality was 25 % In thereseeted patients (4 in 16). 3 oí them due to disrup!ion of the anastomosis. 5 patients have survived (average 26.4 months) , and 6 oí them have d ied (average, 15 monlhs after su.rgery) . Global survivnl of the serie!; up 10 ' he moment has been 20 months.


Los autores preconizan un ta"atamiento corobinado mediante radioterapia preoperatoria y cirugía, frente a enfermos con cáncer del esófago. Administran, mediante fuente de cobalto 60 y técnica preferentemente rotatoria, una dosis de 4000 rads en 3 semanas, en un campo amplio, de 8 cm de ancho y 15 cm o más de altura, centrado por la lesión. No haeen in"adiación total del e'Sófago, ni tampoco de la. región celiaca. En un plazo de 2 semanas posterior al cese de la radioter-apia, realizan la esofagectomía con gastreetomía proximal y vaciamiento celiaco, por vía torácica iz(!uierda única, para los tumores yuxtafrénicos; por vía combinada, abdominal y luego torácica derecha, para los del tereio medio o superiores del tercio inferior. I.la reconstruceión la realizan en todos Los casos mediante ascens·o gástrico y e~ogastrostom:!:a. De 18 enfennos así tratados, se resecaron 16 (88 %). La mortalidad operatoria fue elel 25 % en los resecados (4 en 16), 3 de ellos por fistulización de la anastomosis. 5 enfermos sobreviven (promedio d·e 26,4 meses) y 6 fallecieron (promedialmente a los 15 meses de operados). IJa sohrevida global de la serie, hasta el momento1 es de 20 meses.


Detalles Bibliográficos
1975
radioterapia
esófago
tumores
radiotherapy
esophagus
tumors
Español
Sociedad de Cirugía del Uruguay
Revista Cirugía del Uruguay
https://revista.scu.org.uy/index.php/cir_urug/article/view/2860
Acceso abierto
Resumen:
Sumario:The authors suggest a eombined treatmcnt of preoperative irradiation and surgical excision for patients with careinoma of tbe esophagus. Wlth cobalt-60 gammo. rays thy give a dose of 4000 rads jn 3 weeks, in a large fieId, 8 cm wide and 15 cm or more high, centered by the lesiono They do not carry out a total irradiation oí the esophagus, nOr oí tbe celiac regian. 2 wceks aíter discontinuing radiotherapy, they perform the eso· phagectorny with proximal gastrectomy and celiae Iymph nodes excision by a single left thoraeic approach for juxtufreoie tumors, and by a combined approaCh, abdo· minal and right thoracie, for the tumors of the ntlddlc third or the uppcr ones of the lower third. In all cases continulty was restored by intrathoracic esophago-gastrostomy. Out oi. the 18 p;\tients thus treated 16 were res~cted (88 % ). Operative mortality was 25 % In thereseeted patients (4 in 16). 3 oí them due to disrup!ion of the anastomosis. 5 patients have survived (average 26.4 months) , and 6 oí them have d ied (average, 15 monlhs after su.rgery) . Global survivnl of the serie!; up 10 ' he moment has been 20 months.