Inflammatory breast cancer Clinical presentation Value of combined treatments

Cáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinados

Viola Alles, Alberto - Sabini, Graciela - Barrios, Enrique - Musé, Miguel

Resumen:

Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.


Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea.


Detalles Bibliográficos
1995
cáncer de mama
tumores
breast cancer
tumors
Español
Sociedad de Cirugía del Uruguay
Revista Cirugía del Uruguay
https://revista.scu.org.uy/index.php/cir_urug/article/view/4190
Acceso abierto
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author Viola Alles, Alberto
author2 Sabini, Graciela
Barrios, Enrique
Musé, Miguel
author2_role author
author
author
author_facet Viola Alles, Alberto
Sabini, Graciela
Barrios, Enrique
Musé, Miguel
author_role author
collection Revista Cirugía del Uruguay
dc.creator.none.fl_str_mv Viola Alles, Alberto
Sabini, Graciela
Barrios, Enrique
Musé, Miguel
dc.date.none.fl_str_mv 1995-04-18
dc.description.abstract.none.fl_txt_mv Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.
Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea.
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://revista.scu.org.uy/index.php/cir_urug/article/view/4190
dc.language.iso.none.fl_str_mv spa
dc.publisher.none.fl_str_mv Sociedad de Cirugía del Uruguay
dc.relation.none.fl_str_mv https://revista.scu.org.uy/index.php/cir_urug/article/view/4190/3944
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.source.none.fl_str_mv Revista Cirugía del Uruguay; Vol. 65 No. 2 (1995): Cirugía del Uruguay; 111-116
Revista Cirugía del Uruguay; Vol. 65 Núm. 2 (1995): Cirugía del Uruguay; 111-116
1688-1281
reponame:Revista Cirugía del Uruguay
instname:Sociedad de Cirugía del Uruguay
instacron:Sociedad de Cirugía del Uruguay
dc.subject.none.fl_str_mv cáncer de mama
tumores
breast cancer
tumors
dc.title.none.fl_str_mv Inflammatory breast cancer Clinical presentation Value of combined treatments
Cáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinados
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
description Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.
eu_rights_str_mv openAccess
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publishDate 1995
publisher.none.fl_str_mv Sociedad de Cirugía del Uruguay
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spelling Inflammatory breast cancer Clinical presentation Value of combined treatmentsCáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinadosViola Alles, AlbertoSabini, GracielaBarrios, EnriqueMusé, Miguelcáncer de mamatumoresbreast cancertumorsOver a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea.Sociedad de Cirugía del Uruguay1995-04-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revista.scu.org.uy/index.php/cir_urug/article/view/4190Revista Cirugía del Uruguay; Vol. 65 No. 2 (1995): Cirugía del Uruguay; 111-116Revista Cirugía del Uruguay; Vol. 65 Núm. 2 (1995): Cirugía del Uruguay; 111-1161688-1281reponame:Revista Cirugía del Uruguayinstname:Sociedad de Cirugía del Uruguayinstacron:Sociedad de Cirugía del Uruguayspahttps://revista.scu.org.uy/index.php/cir_urug/article/view/4190/3944info:eu-repo/semantics/openAccess2021-04-18T05:03:34Zoai:ojs2.revista.scu.org.uy:article/4190Privadahttps://scu.org.uy/https://revista.scu.org.uy/index.php/cir_urug/oaiUruguayopendoar:2021-04-18T05:03:34Revista Cirugía del Uruguay - Sociedad de Cirugía del Uruguayfalse
spellingShingle Inflammatory breast cancer Clinical presentation Value of combined treatments
Viola Alles, Alberto
cáncer de mama
tumores
breast cancer
tumors
status_str publishedVersion
title Inflammatory breast cancer Clinical presentation Value of combined treatments
title_full Inflammatory breast cancer Clinical presentation Value of combined treatments
title_fullStr Inflammatory breast cancer Clinical presentation Value of combined treatments
title_full_unstemmed Inflammatory breast cancer Clinical presentation Value of combined treatments
title_short Inflammatory breast cancer Clinical presentation Value of combined treatments
title_sort Inflammatory breast cancer Clinical presentation Value of combined treatments
topic cáncer de mama
tumores
breast cancer
tumors
url https://revista.scu.org.uy/index.php/cir_urug/article/view/4190