Inflammatory breast cancer Clinical presentation Value of combined treatments
Cáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinados
Resumen:
Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.
Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea.
1995 | |
cáncer de mama tumores breast cancer tumors |
|
Español | |
Sociedad de Cirugía del Uruguay | |
Revista Cirugía del Uruguay | |
https://revista.scu.org.uy/index.php/cir_urug/article/view/4190 | |
Acceso abierto |
_version_ | 1815772780866568192 |
---|---|
author | Viola Alles, Alberto |
author2 | Sabini, Graciela Barrios, Enrique Musé, Miguel |
author2_role | author author author |
author_facet | Viola Alles, Alberto Sabini, Graciela Barrios, Enrique Musé, Miguel |
author_role | author |
collection | Revista Cirugía del Uruguay |
dc.creator.none.fl_str_mv | Viola Alles, Alberto Sabini, Graciela Barrios, Enrique Musé, Miguel |
dc.date.none.fl_str_mv | 1995-04-18 |
dc.description.abstract.none.fl_txt_mv | Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant. Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea. |
dc.format.none.fl_str_mv | application/pdf |
dc.identifier.none.fl_str_mv | https://revista.scu.org.uy/index.php/cir_urug/article/view/4190 |
dc.language.iso.none.fl_str_mv | spa |
dc.publisher.none.fl_str_mv | Sociedad de Cirugía del Uruguay |
dc.relation.none.fl_str_mv | https://revista.scu.org.uy/index.php/cir_urug/article/view/4190/3944 |
dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
dc.source.none.fl_str_mv | Revista Cirugía del Uruguay; Vol. 65 No. 2 (1995): Cirugía del Uruguay; 111-116 Revista Cirugía del Uruguay; Vol. 65 Núm. 2 (1995): Cirugía del Uruguay; 111-116 1688-1281 reponame:Revista Cirugía del Uruguay instname:Sociedad de Cirugía del Uruguay instacron:Sociedad de Cirugía del Uruguay |
dc.subject.none.fl_str_mv | cáncer de mama tumores breast cancer tumors |
dc.title.none.fl_str_mv | Inflammatory breast cancer Clinical presentation Value of combined treatments Cáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinados |
dc.type.none.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
description | Over a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant. |
eu_rights_str_mv | openAccess |
format | article |
id | SCU_1_145ab1bdedfff503982408b67e95283a |
instacron_str | Sociedad de Cirugía del Uruguay |
institution | Sociedad de Cirugía del Uruguay |
instname_str | Sociedad de Cirugía del Uruguay |
language | spa |
network_acronym_str | SCU_1 |
network_name_str | Revista Cirugía del Uruguay |
oai_identifier_str | oai:ojs2.revista.scu.org.uy:article/4190 |
publishDate | 1995 |
publisher.none.fl_str_mv | Sociedad de Cirugía del Uruguay |
reponame_str | Revista Cirugía del Uruguay |
repository.mail.fl_str_mv | |
repository.name.fl_str_mv | Revista Cirugía del Uruguay - Sociedad de Cirugía del Uruguay |
repository_id_str | |
spelling | Inflammatory breast cancer Clinical presentation Value of combined treatmentsCáncer inflamatorio de mama Presentación clínica Valor de los tratamientos combinadosViola Alles, AlbertoSabini, GracielaBarrios, EnriqueMusé, Miguelcáncer de mamatumoresbreast cancertumorsOver a total of 1152 patients carrying breas/ cancer whowere treated between 1978 and 1988, 41 cases (3,5%)corresponded to the inf/ammatory variety Their agesranged between 26 and 73 years; 15 (63,5 %) werefound in postmenopausica/ women. From the clinicalpoint of view, in 34, 1 % of the cases the disease waslimited to the breast exclusive/y; 48, 7% presentedregional invasion of nades and the remainig 17%presented disseminated disease. lnitial treatmentconsisted of 3-4 chemotherapy cycles of the FAC typeexcept in the case of elderly patients who a/so receivedCMF association. Al/ of them were la ter radiated withdoses of 5000-6000 cGy over breas/ and nadeterritories. Treatment ended with 6 to 8 additionalchemoterapy cycles. None of the patients underwentsurgery. Median survival of the whole population was of22 months (26 far premenopausica/ patients and 15 farthe postmenopausical ones). Recidive percentage roseas 30%, 45% of the localized forms disseminated in theevolution. The authors emphasize the fact that thetherapeutical strategy was based on chemo-radiotherapyassociation; there is a possibility of management withhigh doses of cytostatic agents with or without bonemarrow transplant.Sobre un total de 1152 pacientes portadoras de cáncerde mama, tratadas en el período 1978-1988, 41 de ellas(3,5%) correspondieron a la variedad inflamatoria.Sus edades estaban comprendidas entre 26 y 73 años;siendo 15 (63,5%) posmenopáusicas.Clínicamente presentaron compromiso mamarioexclusivo 34, 1 %; invasión ganglionar locorregional48, 7% y estaban diseminadas 17% restantes. Eltratamiento inicial se basó en 3-4 ciclos de quimioterapiatipo FAC; salvo en pacientes añosas que recibieron laasociación CMF Todas ellas luego se irradiaron condosis de 5000-6000 cGy sobre mama y territoriosganglionares. Se culminó el tratamiento con 6 a 8 ciclosadicionales de quimioterapia. Ninguna de las pacientesfue sometida a cirugía. La sobrevida media del total de lapoblación fue de 22 meses, siendo de 26 para laspremenopáusicas y 15 para las posmenopáusicas. Elporcentaje de recidivas llegó al 30%; y 45% de lasformas localizadas se diseminaron durante su evolución.Se destaca que la estrategia terapéutica se basó en laasociación quimio-radioterapia, quedando abierta laposibilidad del manejo de altas dosis de citos/áticos cono sin trasplante de médula ósea.Sociedad de Cirugía del Uruguay1995-04-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revista.scu.org.uy/index.php/cir_urug/article/view/4190Revista Cirugía del Uruguay; Vol. 65 No. 2 (1995): Cirugía del Uruguay; 111-116Revista Cirugía del Uruguay; Vol. 65 Núm. 2 (1995): Cirugía del Uruguay; 111-1161688-1281reponame:Revista Cirugía del Uruguayinstname:Sociedad de Cirugía del Uruguayinstacron:Sociedad de Cirugía del Uruguayspahttps://revista.scu.org.uy/index.php/cir_urug/article/view/4190/3944info:eu-repo/semantics/openAccess2021-04-18T05:03:34Zoai:ojs2.revista.scu.org.uy:article/4190Privadahttps://scu.org.uy/https://revista.scu.org.uy/index.php/cir_urug/oaiUruguayopendoar:2021-04-18T05:03:34Revista Cirugía del Uruguay - Sociedad de Cirugía del Uruguayfalse |
spellingShingle | Inflammatory breast cancer Clinical presentation Value of combined treatments Viola Alles, Alberto cáncer de mama tumores breast cancer tumors |
status_str | publishedVersion |
title | Inflammatory breast cancer Clinical presentation Value of combined treatments |
title_full | Inflammatory breast cancer Clinical presentation Value of combined treatments |
title_fullStr | Inflammatory breast cancer Clinical presentation Value of combined treatments |
title_full_unstemmed | Inflammatory breast cancer Clinical presentation Value of combined treatments |
title_short | Inflammatory breast cancer Clinical presentation Value of combined treatments |
title_sort | Inflammatory breast cancer Clinical presentation Value of combined treatments |
topic | cáncer de mama tumores breast cancer tumors |
url | https://revista.scu.org.uy/index.php/cir_urug/article/view/4190 |