Treatment of locally advanced rectal cancer with radiation therapy and preoperative chemotherapy

Tratamiento del cáncer de recto localmente avanzado con radioterapia y quimioterapia preoperatoria

Luongo, Alvaro - Aguiar, Sergio - González Machado, Luis - Guerra, José - Michelenea, Carlos - Bisio, Hugo - Ruiz Liard, Claudio - Varangot, Mario - Wolman, Roberto - Kasdorf, Pedro - García, Silvia - Tasende, Blanca - Echenique, Maria - Torres, Miguel - Lusheimer, Daniel - Hernández, Walter - Delgado, Fernando

Resumen:

Colorectal cancer has a high mortality rafe in Uruguay Surgery alone has a local relapsing rafe of 13-26%. Preoperative irradia/ion has shown to improve the ressecability and the local management. The aim of this protocol is to decrease the rafe of local relapse, using preopeative raiotherapy (RT) and concomitan/ chemoterapy that enhances the RT effects, improving therefore the therapeutic ratio.


En Uruguay, el cáncer colorrectal tiene una alta tasa de mortalidad. La cirugía exclusiva, tiene 13-26% de recurrencias locales. La irradiación preoperatoria ha demostrado mejorar la resecabilidad y el control local. El objetivo de este protocolo es disminuir el porcentaje de recidiva local, utilizando radioterapia (RT) preoperatoria y quimioterapia concomitante que potencie el efecto de la RT, mejorando así el cociente terapéutico.


Detalles Bibliográficos
1993
neoplasmas
quimioterapia
radioterapia
recto
neoplasms
chemotherapy
radiotherapy
rectum
Español
Sociedad de Cirugía del Uruguay
Revista Cirugía del Uruguay
https://revista.scu.org.uy/index.php/cir_urug/article/view/4228
Acceso abierto
Resumen:
Sumario:Colorectal cancer has a high mortality rafe in Uruguay Surgery alone has a local relapsing rafe of 13-26%. Preoperative irradia/ion has shown to improve the ressecability and the local management. The aim of this protocol is to decrease the rafe of local relapse, using preopeative raiotherapy (RT) and concomitan/ chemoterapy that enhances the RT effects, improving therefore the therapeutic ratio.