Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications
Resumen:
This study evaluated the use of autohydrolysis as a green method to extract biophenols with antioxidant and antibiofilm activities from Uruguayan olive pomace (OP), considering the formation of degradation compounds such as 5-hydroxymethylfurfural (HMF). Response surface methodology was utilized to evaluate the effect of temperature, extraction time and liquid-solid ratio on extraction yield (EY), total phenolic content (TPC), antioxidant activity (FRAP and DPPH assays), hydroxytyrosol (HTY) content and HMF content. The optimal extraction conditions (168 °C, 24 min, and liquid-solid ratio of 20 mL/g) were determined to maximize EY (25.65 g/100 g), TPC (28.60 mgGAE/g), antioxidant activity (FRAP: 328.50 µmolFSE/g; DPPH: 122.33 µmolTRE/g) and HTY content (2.79 mg/g) while minimizing HMF content (0.92 mg/g). Under these conditions, the obtained extract showed greater protection for sunflower oil than the synthetic antioxidants tested (BHA and BHT) and demonstrated the ability to inhibit biofilm formation of Candida albicans and Staphylococcus aureus.
| 2026 | |
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Agencia Nacional de Investigación e Innovación Universidad de la República. Comisión Académica de Posgrado Universidad de la República. Comisión Sectorial de Investigación Científica |
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5-hydroxymethylfurfural Antibiofilm Antioxidants Autohydrolysis Hydroxytyrosol Olive pomace Ingeniería y Tecnología Ingeniería Química Ciencias Naturales y Exactas Ciencias Biológicas Otros Tópicos Biológicos |
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| Inglés | |
| Agencia Nacional de Investigación e Innovación | |
| REDI | |
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https://hdl.handle.net/20.500.12381/5594
https://doi.org/10.3989/gya.0213251.2292 |
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| Acceso abierto | |
| Reconocimiento 4.0 Internacional. (CC BY) |
| _version_ | 1881638706507415552 |
|---|---|
| author | Cabrera, Leandro |
| author2 | Xavier, Lucía Vieitez, Ignacio Raffaelli, Sofía Alborés, Silvana Zecchi, Berta |
| author2_role | author author author author author |
| author_facet | Cabrera, Leandro Xavier, Lucía Vieitez, Ignacio Raffaelli, Sofía Alborés, Silvana Zecchi, Berta |
| author_role | author |
| bitstream.checksum.fl_str_mv | a4ce09f01b5dd771727aa05c73851623 3da95cb595444eb4937d4f53c0fa8db0 |
| bitstream.checksumAlgorithm.fl_str_mv | MD5 MD5 |
| bitstream.url.fl_str_mv | https://redi.anii.org.uy/jspui/bitstream/20.500.12381/5594/2/license.txt https://redi.anii.org.uy/jspui/bitstream/20.500.12381/5594/1/cabrera2025.pdf |
| collection | REDI |
| dc.creator.none.fl_str_mv | Cabrera, Leandro Xavier, Lucía Vieitez, Ignacio Raffaelli, Sofía Alborés, Silvana Zecchi, Berta |
| dc.date.accessioned.none.fl_str_mv | 2026-06-17T17:43:11Z |
| dc.date.available.none.fl_str_mv | 2026-06-17T17:43:11Z |
| dc.date.issued.none.fl_str_mv | 2026-02 |
| dc.description.abstract.none.fl_txt_mv | This study evaluated the use of autohydrolysis as a green method to extract biophenols with antioxidant and antibiofilm activities from Uruguayan olive pomace (OP), considering the formation of degradation compounds such as 5-hydroxymethylfurfural (HMF). Response surface methodology was utilized to evaluate the effect of temperature, extraction time and liquid-solid ratio on extraction yield (EY), total phenolic content (TPC), antioxidant activity (FRAP and DPPH assays), hydroxytyrosol (HTY) content and HMF content. The optimal extraction conditions (168 °C, 24 min, and liquid-solid ratio of 20 mL/g) were determined to maximize EY (25.65 g/100 g), TPC (28.60 mgGAE/g), antioxidant activity (FRAP: 328.50 µmolFSE/g; DPPH: 122.33 µmolTRE/g) and HTY content (2.79 mg/g) while minimizing HMF content (0.92 mg/g). Under these conditions, the obtained extract showed greater protection for sunflower oil than the synthetic antioxidants tested (BHA and BHT) and demonstrated the ability to inhibit biofilm formation of Candida albicans and Staphylococcus aureus. |
| dc.description.sponsorship.none.fl_txt_mv | Agencia Nacional de Investigación e Innovación Universidad de la República. Comisión Académica de Posgrado Universidad de la República. Comisión Sectorial de Investigación Científica |
| dc.identifier.anii.es.fl_str_mv | POS_NAC_2018_1_151628 |
| dc.identifier.doi.none.fl_str_mv | https://doi.org/10.3989/gya.0213251.2292 |
| dc.identifier.uri.none.fl_str_mv | https://hdl.handle.net/20.500.12381/5594 |
| dc.language.iso.none.fl_str_mv | eng |
| dc.publisher.es.fl_str_mv | Consejo Superior de Investigaciones Científicas |
| dc.relation.none.fl_str_mv | https://hdl.handle.net/20.500.12381/5595 https://hdl.handle.net/20.500.12381/5596 https://hdl.handle.net/20.500.12381/5597 https://hdl.handle.net/20.500.12381/5598 |
| dc.rights.*.fl_str_mv | Acceso abierto |
| dc.rights.license.none.fl_str_mv | Reconocimiento 4.0 Internacional. (CC BY) |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.es.fl_str_mv | Grasas y Aceites |
| dc.source.none.fl_str_mv | reponame:REDI instname:Agencia Nacional de Investigación e Innovación instacron:Agencia Nacional de Investigación e Innovación |
| dc.subject.anii.none.fl_str_mv | Ingeniería y Tecnología Ingeniería Química Ciencias Naturales y Exactas Ciencias Biológicas Otros Tópicos Biológicos |
| dc.subject.es.fl_str_mv | 5-hydroxymethylfurfural Antibiofilm Antioxidants Autohydrolysis Hydroxytyrosol Olive pomace |
| dc.title.none.fl_str_mv | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| dc.type.es.fl_str_mv | Artículo |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.version.es.fl_str_mv | Publicado |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | This study evaluated the use of autohydrolysis as a green method to extract biophenols with antioxidant and antibiofilm activities from Uruguayan olive pomace (OP), considering the formation of degradation compounds such as 5-hydroxymethylfurfural (HMF). Response surface methodology was utilized to evaluate the effect of temperature, extraction time and liquid-solid ratio on extraction yield (EY), total phenolic content (TPC), antioxidant activity (FRAP and DPPH assays), hydroxytyrosol (HTY) content and HMF content. The optimal extraction conditions (168 °C, 24 min, and liquid-solid ratio of 20 mL/g) were determined to maximize EY (25.65 g/100 g), TPC (28.60 mgGAE/g), antioxidant activity (FRAP: 328.50 µmolFSE/g; DPPH: 122.33 µmolTRE/g) and HTY content (2.79 mg/g) while minimizing HMF content (0.92 mg/g). Under these conditions, the obtained extract showed greater protection for sunflower oil than the synthetic antioxidants tested (BHA and BHT) and demonstrated the ability to inhibit biofilm formation of Candida albicans and Staphylococcus aureus. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | REDI_2bd043f37fad6ef664fdbfc0d4f430ce |
| identifier_str_mv | POS_NAC_2018_1_151628 |
| instacron_str | Agencia Nacional de Investigación e Innovación |
| institution | Agencia Nacional de Investigación e Innovación |
| instname_str | Agencia Nacional de Investigación e Innovación |
| language | eng |
| network_acronym_str | REDI |
| network_name_str | REDI |
| oai_identifier_str | oai:redi.anii.org.uy:20.500.12381/5594 |
| publishDate | 2026 |
| reponame_str | REDI |
| repository.mail.fl_str_mv | jmaldini@anii.org.uy |
| repository.name.fl_str_mv | REDI - Agencia Nacional de Investigación e Innovación |
| repository_id_str | 9421 |
| rights_invalid_str_mv | Reconocimiento 4.0 Internacional. (CC BY) Acceso abierto |
| spelling | Reconocimiento 4.0 Internacional. (CC BY)Acceso abiertoinfo:eu-repo/semantics/openAccess2026-06-17T17:43:11Z2026-06-17T17:43:11Z2026-02https://hdl.handle.net/20.500.12381/5594POS_NAC_2018_1_151628https://doi.org/10.3989/gya.0213251.2292This study evaluated the use of autohydrolysis as a green method to extract biophenols with antioxidant and antibiofilm activities from Uruguayan olive pomace (OP), considering the formation of degradation compounds such as 5-hydroxymethylfurfural (HMF). Response surface methodology was utilized to evaluate the effect of temperature, extraction time and liquid-solid ratio on extraction yield (EY), total phenolic content (TPC), antioxidant activity (FRAP and DPPH assays), hydroxytyrosol (HTY) content and HMF content. The optimal extraction conditions (168 °C, 24 min, and liquid-solid ratio of 20 mL/g) were determined to maximize EY (25.65 g/100 g), TPC (28.60 mgGAE/g), antioxidant activity (FRAP: 328.50 µmolFSE/g; DPPH: 122.33 µmolTRE/g) and HTY content (2.79 mg/g) while minimizing HMF content (0.92 mg/g). Under these conditions, the obtained extract showed greater protection for sunflower oil than the synthetic antioxidants tested (BHA and BHT) and demonstrated the ability to inhibit biofilm formation of Candida albicans and Staphylococcus aureus.Agencia Nacional de Investigación e InnovaciónUniversidad de la República. Comisión Académica de PosgradoUniversidad de la República. Comisión Sectorial de Investigación CientíficaengConsejo Superior de Investigaciones Científicashttps://hdl.handle.net/20.500.12381/5595https://hdl.handle.net/20.500.12381/5596https://hdl.handle.net/20.500.12381/5597https://hdl.handle.net/20.500.12381/5598Grasas y Aceitesreponame:REDIinstname:Agencia Nacional de Investigación e Innovacióninstacron:Agencia Nacional de Investigación e Innovación5-hydroxymethylfurfuralAntibiofilmAntioxidantsAutohydrolysisHydroxytyrosolOlive pomaceIngeniería y TecnologíaIngeniería QuímicaCiencias Naturales y ExactasCiencias BiológicasOtros Tópicos BiológicosGreen extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applicationsArtículoPublicadoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidad de la República. Facultad de Ingeniería//Ingeniería y Tecnología/Ingeniería Química/Ingeniería Química//Ciencias Naturales y Exactas/Ciencias Biológicas/Otros Tópicos BiológicosCabrera, LeandroXavier, LucíaVieitez, IgnacioRaffaelli, SofíaAlborés, SilvanaZecchi, BertaLICENSElicense.txtlicense.txttext/plain; charset=utf-84967https://redi.anii.org.uy/jspui/bitstream/20.500.12381/5594/2/license.txta4ce09f01b5dd771727aa05c73851623MD52ORIGINALcabrera2025.pdfcabrera2025.pdfapplication/pdf1596382https://redi.anii.org.uy/jspui/bitstream/20.500.12381/5594/1/cabrera2025.pdf3da95cb595444eb4937d4f53c0fa8db0MD5120.500.12381/55942026-06-18 11:25:58.025oai:redi.anii.org.uy:20.500.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Institucionalhttps://redi.anii.org.uy/Gobiernohttps://www.anii.org.uy/https://redi.anii.org.uy/oai/requestjmaldini@anii.org.uyUruguayopendoar:94212026-06-18T14:25:58REDI - Agencia Nacional de Investigación e Innovaciónfalse |
| spellingShingle | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications Cabrera, Leandro 5-hydroxymethylfurfural Antibiofilm Antioxidants Autohydrolysis Hydroxytyrosol Olive pomace Ingeniería y Tecnología Ingeniería Química Ciencias Naturales y Exactas Ciencias Biológicas Otros Tópicos Biológicos |
| status_str | publishedVersion |
| title | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| title_full | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| title_fullStr | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| title_full_unstemmed | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| title_short | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| title_sort | Green extraction of phenolic compounds from olive pomace: optimization of autohydrolysis conditions and evaluation of potential applications |
| topic | 5-hydroxymethylfurfural Antibiofilm Antioxidants Autohydrolysis Hydroxytyrosol Olive pomace Ingeniería y Tecnología Ingeniería Química Ciencias Naturales y Exactas Ciencias Biológicas Otros Tópicos Biológicos |
| url | https://hdl.handle.net/20.500.12381/5594 https://doi.org/10.3989/gya.0213251.2292 |
