Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep.
Resumen:
ABSTRACT.- The objective of this study was to identify genomic regions and genes associated with resistance to gastrointestinal nematodes in Australian Merino sheep in Uruguay, using the single-step GWAS methodology (ssGWAS), which is based on genomic estimated breeding values (GEBVs) obtained from a combination of pedigree, genomic, and phenotypic data. This methodology converts GEBVs into SNP effects. The analysis included 26,638 animals with fecal egg count (FEC) records obtained in two independent parasitic cycles (FEC1 and FEC2) and 1700 50K SNP genotypes. © 2024 by the authors.
| 2024 | |
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SsGBLUP SsGWAS Ovis aries Haemonchus contortus Nematodes SISTEMA GANADERO EXTENSIVO - INIA |
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| Inglés | |
| Instituto Nacional de Investigación Agropecuaria | |
| AINFO | |
| https://ainfo.inia.uy/consulta/busca?b=pc&id=64792&biblioteca=vazio&busca=64792&qFacets=64792 | |
| Acceso abierto |
| _version_ | 1856772321167015936 |
|---|---|
| author | VERA, B. |
| author2 | NAVAJAS, E. PERAZA, P. CARRACELAS, B. VAN LIER, E. CIAPPESONI, G. |
| author2_role | author author author author author |
| author_facet | VERA, B. NAVAJAS, E. PERAZA, P. CARRACELAS, B. VAN LIER, E. CIAPPESONI, G. |
| author_role | author |
| bitstream.checksum.fl_str_mv | 0cb63ff14fc5c1409205456ee4ea060f |
| bitstream.checksumAlgorithm.fl_str_mv | MD5 |
| bitstream.url.fl_str_mv | https://redi.anii.org.uy/jspui/bitstream/20.500.12381/4847/1/sword-2025-06-23T15%3a42%3a59.original.xml |
| collection | AINFO |
| dc.creator.none.fl_str_mv | VERA, B. NAVAJAS, E. PERAZA, P. CARRACELAS, B. VAN LIER, E. CIAPPESONI, G. |
| dc.date.accessioned.none.fl_str_mv | 2025-06-23T18:42:59Z |
| dc.date.available.none.fl_str_mv | 2025-06-23T18:42:59Z |
| dc.date.issued.none.fl_str_mv | 2024 |
| dc.date.updated.none.fl_str_mv | 2025-06-23T18:42:59Z |
| dc.description.abstract.none.fl_txt_mv | ABSTRACT.- The objective of this study was to identify genomic regions and genes associated with resistance to gastrointestinal nematodes in Australian Merino sheep in Uruguay, using the single-step GWAS methodology (ssGWAS), which is based on genomic estimated breeding values (GEBVs) obtained from a combination of pedigree, genomic, and phenotypic data. This methodology converts GEBVs into SNP effects. The analysis included 26,638 animals with fecal egg count (FEC) records obtained in two independent parasitic cycles (FEC1 and FEC2) and 1700 50K SNP genotypes. © 2024 by the authors. |
| dc.identifier.none.fl_str_mv | https://ainfo.inia.uy/consulta/busca?b=pc&id=64792&biblioteca=vazio&busca=64792&qFacets=64792 |
| dc.language.iso.none.fl_str_mv | en eng |
| dc.rights.es.fl_str_mv | Acceso abierto |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:AINFO instname:Instituto Nacional de Investigación Agropecuaria instacron:Instituto Nacional de Investigación Agropecuaria |
| dc.subject.none.fl_str_mv | SsGBLUP SsGWAS Ovis aries Haemonchus contortus Nematodes SISTEMA GANADERO EXTENSIVO - INIA |
| dc.title.none.fl_str_mv | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| dc.type.none.fl_str_mv | Article PublishedVersion info:eu-repo/semantics/article |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | ABSTRACT.- The objective of this study was to identify genomic regions and genes associated with resistance to gastrointestinal nematodes in Australian Merino sheep in Uruguay, using the single-step GWAS methodology (ssGWAS), which is based on genomic estimated breeding values (GEBVs) obtained from a combination of pedigree, genomic, and phenotypic data. This methodology converts GEBVs into SNP effects. The analysis included 26,638 animals with fecal egg count (FEC) records obtained in two independent parasitic cycles (FEC1 and FEC2) and 1700 50K SNP genotypes. © 2024 by the authors. |
| eu_rights_str_mv | openAccess |
| format | article |
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| instacron_str | Instituto Nacional de Investigación Agropecuaria |
| institution | Instituto Nacional de Investigación Agropecuaria |
| instname_str | Instituto Nacional de Investigación Agropecuaria |
| language | eng |
| language_invalid_str_mv | en |
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| oai_identifier_str | oai:redi.anii.org.uy:20.500.12381/4847 |
| publishDate | 2024 |
| reponame_str | AINFO |
| repository.mail.fl_str_mv | lorrego@inia.org.uy |
| repository.name.fl_str_mv | AINFO - Instituto Nacional de Investigación Agropecuaria |
| repository_id_str | |
| rights_invalid_str_mv | Acceso abierto |
| spelling | 2025-06-23T18:42:59Z2025-06-23T18:42:59Z20242025-06-23T18:42:59Zhttps://ainfo.inia.uy/consulta/busca?b=pc&id=64792&biblioteca=vazio&busca=64792&qFacets=64792ABSTRACT.- The objective of this study was to identify genomic regions and genes associated with resistance to gastrointestinal nematodes in Australian Merino sheep in Uruguay, using the single-step GWAS methodology (ssGWAS), which is based on genomic estimated breeding values (GEBVs) obtained from a combination of pedigree, genomic, and phenotypic data. This methodology converts GEBVs into SNP effects. The analysis included 26,638 animals with fecal egg count (FEC) records obtained in two independent parasitic cycles (FEC1 and FEC2) and 1700 50K SNP genotypes. © 2024 by the authors.https://hdl.handle.net/20.500.12381/4847enenginfo:eu-repo/semantics/openAccessAcceso abiertoSsGBLUPSsGWASOvis ariesHaemonchus contortusNematodesSISTEMA GANADERO EXTENSIVO - INIAGenomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep.ArticlePublishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:AINFOinstname:Instituto Nacional de Investigación Agropecuariainstacron:Instituto Nacional de Investigación AgropecuariaVERA, B.NAVAJAS, E.PERAZA, P.CARRACELAS, B.VAN LIER, E.CIAPPESONI, G.SWORDsword-2025-06-23T15:42:59.original.xmlOriginal SWORD entry documentapplication/octet-stream1862https://redi.anii.org.uy/jspui/bitstream/20.500.12381/4847/1/sword-2025-06-23T15%3a42%3a59.original.xml0cb63ff14fc5c1409205456ee4ea060fMD5120.500.12381/48472026-02-10 15:54:01.227oai:redi.anii.org.uy:20.500.12381/4847Institucionalhttps://ainfo.inia.uy/Organismo científico-tecnológicohttp://inia.uyhttps://redi.anii.org.uy/oai/requestlorrego@inia.org.uyUruguayopendoar:2026-02-10T18:54:01AINFO - Instituto Nacional de Investigación Agropecuariafalse |
| spellingShingle | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. VERA, B. SsGBLUP SsGWAS Ovis aries Haemonchus contortus Nematodes SISTEMA GANADERO EXTENSIVO - INIA |
| status_str | publishedVersion |
| title | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| title_full | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| title_fullStr | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| title_full_unstemmed | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| title_short | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| title_sort | Genomic regions associated with resistance to gastrointestinal parasites in Australian Merino sheep. |
| topic | SsGBLUP SsGWAS Ovis aries Haemonchus contortus Nematodes SISTEMA GANADERO EXTENSIVO - INIA |
| url | https://ainfo.inia.uy/consulta/busca?b=pc&id=64792&biblioteca=vazio&busca=64792&qFacets=64792 |
