Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models.
Resumen:
ABSTRACT.The objective of this study was to compare a conventional genomic model (GBLUP) and its extension to a linear reaction norm model (GLRNM) specifying genotype by environment interaction (G*E) for tick resistance in Brazilian cattle. Tick counts (TC) from 4,363 Hereford and Braford cattle from 146 contemporary groups (CG) were available of which 3,591 animals had BovineSNP50 Illumina v2 BeadChip genotypes. The reaction norm covariate was based on CG estimates of TC from a first-step model. Analysis was conducted based on adapting the single step GBLUP/REML procedure. Five-fold cross validation based on K-means and random partitioning was used to compare the fit of the two models. Cross validation correlations were strong and not significantly different between models for either partitioning strategy. Nevertheless, it seems apparent that G*E for tick infestation exists and can captured by GLRNM models.
| 2014 | |
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Cross validation Single-step Tick counts |
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| Inglés | |
| Instituto Nacional de Investigación Agropecuaria | |
| AINFO | |
| http://www.ainfo.inia.uy/consulta/busca?b=pc&id=61924&biblioteca=vazio&busca=61924&qFacets=61924 | |
| Acceso abierto |
| _version_ | 1805580527147679744 |
|---|---|
| author | MOTA, R.R. |
| author2 | TEMPELMAN, R.J. FERNANDO F CARDOSO AGUILAR, I. LOPES, P.S. |
| author2_role | author author author author |
| author_facet | MOTA, R.R. TEMPELMAN, R.J. FERNANDO F CARDOSO AGUILAR, I. LOPES, P.S. |
| author_role | author |
| bitstream.checksum.fl_str_mv | 18cddaabd6662e31e6ed6fa2f2849630 |
| bitstream.checksumAlgorithm.fl_str_mv | MD5 |
| bitstream.url.fl_str_mv | https://redi.anii.org.uy/jspui/bitstream/20.500.12381/1733/1/sword-2022-10-20T22%3a49%3a02.original.xml |
| collection | AINFO |
| dc.creator.none.fl_str_mv | MOTA, R.R. TEMPELMAN, R.J. FERNANDO F CARDOSO AGUILAR, I. LOPES, P.S. |
| dc.date.accessioned.none.fl_str_mv | 2022-10-21T01:49:02Z |
| dc.date.available.none.fl_str_mv | 2022-10-21T01:49:02Z |
| dc.date.issued.none.fl_str_mv | 2014 |
| dc.date.updated.none.fl_str_mv | 2022-10-21T01:49:02Z |
| dc.description.abstract.none.fl_txt_mv | ABSTRACT.The objective of this study was to compare a conventional genomic model (GBLUP) and its extension to a linear reaction norm model (GLRNM) specifying genotype by environment interaction (G*E) for tick resistance in Brazilian cattle. Tick counts (TC) from 4,363 Hereford and Braford cattle from 146 contemporary groups (CG) were available of which 3,591 animals had BovineSNP50 Illumina v2 BeadChip genotypes. The reaction norm covariate was based on CG estimates of TC from a first-step model. Analysis was conducted based on adapting the single step GBLUP/REML procedure. Five-fold cross validation based on K-means and random partitioning was used to compare the fit of the two models. Cross validation correlations were strong and not significantly different between models for either partitioning strategy. Nevertheless, it seems apparent that G*E for tick infestation exists and can captured by GLRNM models. |
| dc.identifier.none.fl_str_mv | http://www.ainfo.inia.uy/consulta/busca?b=pc&id=61924&biblioteca=vazio&busca=61924&qFacets=61924 |
| dc.language.iso.none.fl_str_mv | en eng |
| dc.rights.es.fl_str_mv | Acceso abierto |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:AINFO instname:Instituto Nacional de Investigación Agropecuaria instacron:Instituto Nacional de Investigación Agropecuaria |
| dc.subject.none.fl_str_mv | Cross validation Single-step Tick counts |
| dc.title.none.fl_str_mv | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| dc.type.none.fl_str_mv | ConferenceObject PublishedVersion info:eu-repo/semantics/conferenceObject |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | ABSTRACT.The objective of this study was to compare a conventional genomic model (GBLUP) and its extension to a linear reaction norm model (GLRNM) specifying genotype by environment interaction (G*E) for tick resistance in Brazilian cattle. Tick counts (TC) from 4,363 Hereford and Braford cattle from 146 contemporary groups (CG) were available of which 3,591 animals had BovineSNP50 Illumina v2 BeadChip genotypes. The reaction norm covariate was based on CG estimates of TC from a first-step model. Analysis was conducted based on adapting the single step GBLUP/REML procedure. Five-fold cross validation based on K-means and random partitioning was used to compare the fit of the two models. Cross validation correlations were strong and not significantly different between models for either partitioning strategy. Nevertheless, it seems apparent that G*E for tick infestation exists and can captured by GLRNM models. |
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| instacron_str | Instituto Nacional de Investigación Agropecuaria |
| institution | Instituto Nacional de Investigación Agropecuaria |
| instname_str | Instituto Nacional de Investigación Agropecuaria |
| language | eng |
| language_invalid_str_mv | en |
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| oai_identifier_str | oai:redi.anii.org.uy:20.500.12381/1733 |
| publishDate | 2014 |
| reponame_str | AINFO |
| repository.mail.fl_str_mv | lorrego@inia.org.uy |
| repository.name.fl_str_mv | AINFO - Instituto Nacional de Investigación Agropecuaria |
| repository_id_str | |
| rights_invalid_str_mv | Acceso abierto |
| spelling | 2022-10-21T01:49:02Z2022-10-21T01:49:02Z20142022-10-21T01:49:02Zhttp://www.ainfo.inia.uy/consulta/busca?b=pc&id=61924&biblioteca=vazio&busca=61924&qFacets=61924ABSTRACT.The objective of this study was to compare a conventional genomic model (GBLUP) and its extension to a linear reaction norm model (GLRNM) specifying genotype by environment interaction (G*E) for tick resistance in Brazilian cattle. Tick counts (TC) from 4,363 Hereford and Braford cattle from 146 contemporary groups (CG) were available of which 3,591 animals had BovineSNP50 Illumina v2 BeadChip genotypes. The reaction norm covariate was based on CG estimates of TC from a first-step model. Analysis was conducted based on adapting the single step GBLUP/REML procedure. Five-fold cross validation based on K-means and random partitioning was used to compare the fit of the two models. Cross validation correlations were strong and not significantly different between models for either partitioning strategy. Nevertheless, it seems apparent that G*E for tick infestation exists and can captured by GLRNM models.https://hdl.handle.net/20.500.12381/1733enenginfo:eu-repo/semantics/openAccessAcceso abiertoCross validationSingle-stepTick countsGenomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models.ConferenceObjectPublishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/publishedVersionreponame:AINFOinstname:Instituto Nacional de Investigación Agropecuariainstacron:Instituto Nacional de Investigación AgropecuariaMOTA, R.R.TEMPELMAN, R.J.FERNANDO F CARDOSOAGUILAR, I.LOPES, P.S.SWORDsword-2022-10-20T22:49:02.original.xmlOriginal SWORD entry documentapplication/octet-stream1997https://redi.anii.org.uy/jspui/bitstream/20.500.12381/1733/1/sword-2022-10-20T22%3a49%3a02.original.xml18cddaabd6662e31e6ed6fa2f2849630MD5120.500.12381/17332022-10-20 22:49:03.035oai:redi.anii.org.uy:20.500.12381/1733Gobiernohttp://inia.uyhttps://redi.anii.org.uy/oai/requestlorrego@inia.org.uyUruguayopendoar:2022-10-21T01:49:03AINFO - Instituto Nacional de Investigación Agropecuariafalse |
| spellingShingle | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. MOTA, R.R. Cross validation Single-step Tick counts |
| status_str | publishedVersion |
| title | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| title_full | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| title_fullStr | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| title_full_unstemmed | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| title_short | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| title_sort | Genomic wide-selection for tick resistance in Hereford and Braford cattle via reaction norm models. |
| topic | Cross validation Single-step Tick counts |
| url | http://www.ainfo.inia.uy/consulta/busca?b=pc&id=61924&biblioteca=vazio&busca=61924&qFacets=61924 |
