Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America
Resumen:
All South American countries from the Southern cone (Argentina, Brazil, Chile, Paraguay and Uruguay) experienced severe COVID-19 epidemic waves during early 2021 driven by the expansion of variants Gamma and Lambda, however, there was an improvement in different epidemic indicators since June 2021. To investigate the impact of national vaccination programs and natural infection on viral transmission in those South American countries, we analyzed the coupling between population mobility and the viral effective reproduction number Rt. Our analyses reveal that population mobility was highly correlated with viral Rt from January to May 2021 in all countries analyzed; but a clear decoupling occurred since May–June 2021, when the rate of viral spread started to be lower than expected from the levels of social interactions. These findings support that populations from the South American Southern cone probably achieved the conditional herd immunity threshold to contain the spread of regional SARS-CoV-2 variants circulating at that time.
2022 | |
Computational models Epidemiology |
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Inglés | |
Universidad de la República | |
COLIBRI | |
https://www.nature.com/articles/s41598-022-10896-4
https://hdl.handle.net/20.500.12008/31367 |
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Acceso abierto | |
Licencia Creative Commons Atribución (CC - By 4.0) |
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author | Fiori, Marcelo |
author2 | Bello, Gonzalo Wschebor, Nicolás Lecumberry, Federico Ferragut, Andrés Mordecki, Ernesto |
author2_role | author author author author author |
author_facet | Fiori, Marcelo Bello, Gonzalo Wschebor, Nicolás Lecumberry, Federico Ferragut, Andrés Mordecki, Ernesto |
author_role | author |
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collection | COLIBRI |
dc.contributor.filiacion.none.fl_str_mv | Fiori Marcelo, Universidad de la República (Uruguay). Facultad de Ingeniería. Bello Gonzalo, Laboratorio de AIDS e Imunologia Molecular. Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil Wschebor Nicolás, Universidad de la República (Uruguay). Facultad de Ingeniería. Lecumberry Federico, Universidad de la República (Uruguay). Facultad de Ingeniería. Ferragut Andrés, Universidad ORT (Uruguay). Facultad de Ingeniería Mordecki Ernesto, Universidad de la República (Uruguay). Facultad de Ciencias. |
dc.coverage.spatial.es.fl_str_mv | América del Sur |
dc.coverage.temporal.es.fl_str_mv | 2021 |
dc.creator.none.fl_str_mv | Fiori, Marcelo Bello, Gonzalo Wschebor, Nicolás Lecumberry, Federico Ferragut, Andrés Mordecki, Ernesto |
dc.date.accessioned.none.fl_str_mv | 2022-04-29T11:46:29Z |
dc.date.available.none.fl_str_mv | 2022-04-29T11:46:29Z |
dc.date.issued.none.fl_str_mv | 2022 |
dc.description.abstract.none.fl_txt_mv | All South American countries from the Southern cone (Argentina, Brazil, Chile, Paraguay and Uruguay) experienced severe COVID-19 epidemic waves during early 2021 driven by the expansion of variants Gamma and Lambda, however, there was an improvement in different epidemic indicators since June 2021. To investigate the impact of national vaccination programs and natural infection on viral transmission in those South American countries, we analyzed the coupling between population mobility and the viral effective reproduction number Rt. Our analyses reveal that population mobility was highly correlated with viral Rt from January to May 2021 in all countries analyzed; but a clear decoupling occurred since May–June 2021, when the rate of viral spread started to be lower than expected from the levels of social interactions. These findings support that populations from the South American Southern cone probably achieved the conditional herd immunity threshold to contain the spread of regional SARS-CoV-2 variants circulating at that time. |
dc.format.extent.es.fl_str_mv | 9 p. |
dc.format.mimetype.es.fl_str_mv | application/pdf |
dc.identifier.citation.es.fl_str_mv | Fiori, M., Bello, G., Wschebor, N. y otros. "Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America". Scientific Reports. [en línea]. 2022, vol. 12, 6874, pp. 1-9, DOI: 10.1038/s41598-022-10896-4 |
dc.identifier.doi.none.fl_str_mv | 10.1038/s41598-022-10896-4 |
dc.identifier.issn.none.fl_str_mv | 2045-2322 |
dc.identifier.uri.none.fl_str_mv | https://www.nature.com/articles/s41598-022-10896-4 https://hdl.handle.net/20.500.12008/31367 |
dc.language.iso.none.fl_str_mv | en eng |
dc.publisher.es.fl_str_mv | Springer Nature |
dc.relation.ispartof.es.fl_str_mv | Scientific Reports, Volume 12, Article number 6874, pp 1-9, apr 2022 |
dc.rights.license.none.fl_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
dc.subject.es.fl_str_mv | Computational models Epidemiology |
dc.title.none.fl_str_mv | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
dc.type.es.fl_str_mv | Artículo |
dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
description | All South American countries from the Southern cone (Argentina, Brazil, Chile, Paraguay and Uruguay) experienced severe COVID-19 epidemic waves during early 2021 driven by the expansion of variants Gamma and Lambda, however, there was an improvement in different epidemic indicators since June 2021. To investigate the impact of national vaccination programs and natural infection on viral transmission in those South American countries, we analyzed the coupling between population mobility and the viral effective reproduction number Rt. Our analyses reveal that population mobility was highly correlated with viral Rt from January to May 2021 in all countries analyzed; but a clear decoupling occurred since May–June 2021, when the rate of viral spread started to be lower than expected from the levels of social interactions. These findings support that populations from the South American Southern cone probably achieved the conditional herd immunity threshold to contain the spread of regional SARS-CoV-2 variants circulating at that time. |
eu_rights_str_mv | openAccess |
format | article |
id | COLIBRI_f5763f4bd651c1731cc0f029ac685428 |
identifier_str_mv | Fiori, M., Bello, G., Wschebor, N. y otros. "Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America". Scientific Reports. [en línea]. 2022, vol. 12, 6874, pp. 1-9, DOI: 10.1038/s41598-022-10896-4 2045-2322 10.1038/s41598-022-10896-4 |
instacron_str | Universidad de la República |
institution | Universidad de la República |
instname_str | Universidad de la República |
language | eng |
language_invalid_str_mv | en |
network_acronym_str | COLIBRI |
network_name_str | COLIBRI |
oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/31367 |
publishDate | 2022 |
reponame_str | COLIBRI |
repository.mail.fl_str_mv | mabel.seroubian@seciu.edu.uy |
repository.name.fl_str_mv | COLIBRI - Universidad de la República |
repository_id_str | 4771 |
rights_invalid_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
spelling | Fiori Marcelo, Universidad de la República (Uruguay). Facultad de Ingeniería.Bello Gonzalo, Laboratorio de AIDS e Imunologia Molecular. Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, BrazilWschebor Nicolás, Universidad de la República (Uruguay). Facultad de Ingeniería.Lecumberry Federico, Universidad de la República (Uruguay). Facultad de Ingeniería.Ferragut Andrés, Universidad ORT (Uruguay). Facultad de IngenieríaMordecki Ernesto, Universidad de la República (Uruguay). Facultad de Ciencias.América del Sur20212022-04-29T11:46:29Z2022-04-29T11:46:29Z2022Fiori, M., Bello, G., Wschebor, N. y otros. "Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America". Scientific Reports. [en línea]. 2022, vol. 12, 6874, pp. 1-9, DOI: 10.1038/s41598-022-10896-42045-2322https://www.nature.com/articles/s41598-022-10896-4https://hdl.handle.net/20.500.12008/3136710.1038/s41598-022-10896-4All South American countries from the Southern cone (Argentina, Brazil, Chile, Paraguay and Uruguay) experienced severe COVID-19 epidemic waves during early 2021 driven by the expansion of variants Gamma and Lambda, however, there was an improvement in different epidemic indicators since June 2021. To investigate the impact of national vaccination programs and natural infection on viral transmission in those South American countries, we analyzed the coupling between population mobility and the viral effective reproduction number Rt. Our analyses reveal that population mobility was highly correlated with viral Rt from January to May 2021 in all countries analyzed; but a clear decoupling occurred since May–June 2021, when the rate of viral spread started to be lower than expected from the levels of social interactions. These findings support that populations from the South American Southern cone probably achieved the conditional herd immunity threshold to contain the spread of regional SARS-CoV-2 variants circulating at that time.Submitted by Ribeiro Jorge (jribeiro@fing.edu.uy) on 2022-04-27T17:52:14Z No. of bitstreams: 2 license_rdf: 19875 bytes, checksum: 9fdbed07f52437945402c4e70fa4773e (MD5) FBWLFM22.pdf: 1360979 bytes, checksum: b2dd5ca142eee4355aff0988b46286fa (MD5)Approved for entry into archive by Machado Jimena (jmachado@fing.edu.uy) on 2022-04-28T18:05:48Z (GMT) No. of bitstreams: 2 license_rdf: 19875 bytes, checksum: 9fdbed07f52437945402c4e70fa4773e (MD5) FBWLFM22.pdf: 1360979 bytes, checksum: b2dd5ca142eee4355aff0988b46286fa (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2022-04-29T11:46:29Z (GMT). No. of bitstreams: 2 license_rdf: 19875 bytes, checksum: 9fdbed07f52437945402c4e70fa4773e (MD5) FBWLFM22.pdf: 1360979 bytes, checksum: b2dd5ca142eee4355aff0988b46286fa (MD5) Previous issue date: 20229 p.application/pdfenengSpringer NatureScientific Reports, Volume 12, Article number 6874, pp 1-9, apr 2022Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. 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- Universidad de la Repúblicafalse |
spellingShingle | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America Fiori, Marcelo Computational models Epidemiology |
status_str | publishedVersion |
title | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
title_full | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
title_fullStr | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
title_full_unstemmed | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
title_short | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
title_sort | Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America |
topic | Computational models Epidemiology |
url | https://www.nature.com/articles/s41598-022-10896-4 https://hdl.handle.net/20.500.12008/31367 |