Five challenges in the field of viral diversity and evolution

Sanjuán, Rafael - Illingworth, Christopher J. R. - Geoghegan, Jemma L. - Iranzo, Jaime - Zwart, Mark P. - Ciota, Alexander T. - Gonzalo, Moratorio - Gago-Zachert, Selma - Duffy, Siobain - Vijaykrishna, Dhanasekaran

Resumen:

Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes.


Detalles Bibliográficos
2021
ANII: FCE_1_2019_1156157
ANII: FCE_1_2019_1155930
Virus evolution
Viral metagenomics
Viral phylogenetics
Viral emergence
Evolutionary predictability
Experimental evolution
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/41006
Acceso abierto
Licencia Creative Commons Atribución (CC - By 4.0)

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