Five challenges in the field of viral diversity and evolution
Resumen:
Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes.
| 2021 | |
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ANII: FCE_1_2019_1156157 ANII: FCE_1_2019_1155930 |
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Virus evolution Viral metagenomics Viral phylogenetics Viral emergence Evolutionary predictability Experimental evolution |
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| Inglés | |
| Universidad de la República | |
| COLIBRI | |
| https://hdl.handle.net/20.500.12008/41006 | |
| Acceso abierto | |
| Licencia Creative Commons Atribución (CC - By 4.0) |
| _version_ | 1807522801341431808 |
|---|---|
| author | Sanjuán, Rafael |
| author2 | Illingworth, Christopher J. R. Geoghegan, Jemma L. Iranzo, Jaime Zwart, Mark P. Ciota, Alexander T. Gonzalo, Moratorio Gago-Zachert, Selma Duffy, Siobain Vijaykrishna, Dhanasekaran |
| author2_role | author author author author author author author author author |
| author_facet | Sanjuán, Rafael Illingworth, Christopher J. R. Geoghegan, Jemma L. Iranzo, Jaime Zwart, Mark P. Ciota, Alexander T. Gonzalo, Moratorio Gago-Zachert, Selma Duffy, Siobain Vijaykrishna, Dhanasekaran |
| author_role | author |
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| collection | COLIBRI |
| dc.contributor.filiacion.none.fl_str_mv | Sanjuán Rafael Illingworth Christopher J. R. Geoghegan Jemma L. Iranzo Jaime Zwart Mark P. Ciota Alexander T. Gonzalo Moratorio, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares. Gago-Zachert Selma Duffy Siobain Vijaykrishna Dhanasekaran |
| dc.creator.none.fl_str_mv | Sanjuán, Rafael Illingworth, Christopher J. R. Geoghegan, Jemma L. Iranzo, Jaime Zwart, Mark P. Ciota, Alexander T. Gonzalo, Moratorio Gago-Zachert, Selma Duffy, Siobain Vijaykrishna, Dhanasekaran |
| dc.date.accessioned.none.fl_str_mv | 2023-11-08T15:34:04Z |
| dc.date.available.none.fl_str_mv | 2023-11-08T15:34:04Z |
| dc.date.issued.none.fl_str_mv | 2021 |
| dc.description.abstract.none.fl_txt_mv | Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes. |
| dc.description.sponsorship.none.fl_txt_mv | ANII: FCE_1_2019_1156157 ANII: FCE_1_2019_1155930 |
| dc.format.extent.es.fl_str_mv | 5 h. |
| dc.format.mimetype.es.fl_str_mv | application/pdf |
| dc.identifier.citation.es.fl_str_mv | Sanjuán, R, Illingworth, C, Geoghegan, J [y otros autores] "Five challenges in the field of viral diversity and evolution". Frontiers in Virology. [en línea] 2021, 1: 684949. 5 h. DOI: 10.3389/fviro.2021.684949. |
| dc.identifier.doi.none.fl_str_mv | 10.3389/fviro.2021.684949 |
| dc.identifier.issn.none.fl_str_mv | 2673-818X |
| dc.identifier.uri.none.fl_str_mv | https://hdl.handle.net/20.500.12008/41006 |
| dc.language.iso.none.fl_str_mv | en eng |
| dc.publisher.es.fl_str_mv | Frontiers Media |
| dc.relation.ispartof.es.fl_str_mv | Frontiers in Virology, 2021, 1: 684949. |
| dc.rights.license.none.fl_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.es.fl_str_mv | Virus evolution Viral metagenomics Viral phylogenetics Viral emergence Evolutionary predictability Experimental evolution |
| dc.title.none.fl_str_mv | Five challenges in the field of viral diversity and evolution |
| dc.type.es.fl_str_mv | Artículo |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | COLIBRI_d3fbb524f18c7d6f070725b6c34af64c |
| identifier_str_mv | Sanjuán, R, Illingworth, C, Geoghegan, J [y otros autores] "Five challenges in the field of viral diversity and evolution". Frontiers in Virology. [en línea] 2021, 1: 684949. 5 h. DOI: 10.3389/fviro.2021.684949. 2673-818X 10.3389/fviro.2021.684949 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | COLIBRI |
| network_name_str | COLIBRI |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/41006 |
| publishDate | 2021 |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | mabel.seroubian@seciu.edu.uy |
| repository.name.fl_str_mv | COLIBRI - Universidad de la República |
| repository_id_str | 4771 |
| rights_invalid_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
| spelling | Sanjuán RafaelIllingworth Christopher J. R.Geoghegan Jemma L.Iranzo JaimeZwart Mark P.Ciota Alexander T.Gonzalo Moratorio, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares.Gago-Zachert SelmaDuffy SiobainVijaykrishna Dhanasekaran2023-11-08T15:34:04Z2023-11-08T15:34:04Z2021Sanjuán, R, Illingworth, C, Geoghegan, J [y otros autores] "Five challenges in the field of viral diversity and evolution". Frontiers in Virology. [en línea] 2021, 1: 684949. 5 h. DOI: 10.3389/fviro.2021.684949.2673-818Xhttps://hdl.handle.net/20.500.12008/4100610.3389/fviro.2021.684949Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes.Submitted by Parodi Mónica (mparodi@fcien.edu.uy) on 2023-11-07T20:14:14Z No. of bitstreams: 2 license_rdf: 24251 bytes, checksum: 71ed42ef0a0b648670f707320be37b90 (MD5) 103389fviro2021684949.pdf: 194279 bytes, checksum: fa573c5424a08504fe226163925f4826 (MD5)Approved for entry into archive by Faget Cecilia (lfaget@fcien.edu.uy) on 2023-11-08T15:06:17Z (GMT) No. of bitstreams: 2 license_rdf: 24251 bytes, checksum: 71ed42ef0a0b648670f707320be37b90 (MD5) 103389fviro2021684949.pdf: 194279 bytes, checksum: fa573c5424a08504fe226163925f4826 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2023-11-08T15:34:04Z (GMT). No. of bitstreams: 2 license_rdf: 24251 bytes, checksum: 71ed42ef0a0b648670f707320be37b90 (MD5) 103389fviro2021684949.pdf: 194279 bytes, checksum: fa573c5424a08504fe226163925f4826 (MD5) Previous issue date: 2021ANII: FCE_1_2019_1156157ANII: FCE_1_2019_11559305 h.application/pdfenengFrontiers MediaFrontiers in Virology, 2021, 1: 684949.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución (CC - By 4.0)Virus evolutionViral metagenomicsViral phylogeneticsViral emergenceEvolutionary predictabilityExperimental evolutionFive challenges in the field of viral diversity and evolutionArtículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaSanjuán, RafaelIllingworth, Christopher J. 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- Universidad de la Repúblicafalse |
| spellingShingle | Five challenges in the field of viral diversity and evolution Sanjuán, Rafael Virus evolution Viral metagenomics Viral phylogenetics Viral emergence Evolutionary predictability Experimental evolution |
| status_str | publishedVersion |
| title | Five challenges in the field of viral diversity and evolution |
| title_full | Five challenges in the field of viral diversity and evolution |
| title_fullStr | Five challenges in the field of viral diversity and evolution |
| title_full_unstemmed | Five challenges in the field of viral diversity and evolution |
| title_short | Five challenges in the field of viral diversity and evolution |
| title_sort | Five challenges in the field of viral diversity and evolution |
| topic | Virus evolution Viral metagenomics Viral phylogenetics Viral emergence Evolutionary predictability Experimental evolution |
| url | https://hdl.handle.net/20.500.12008/41006 |
