Experimental study on the probability of inducing and detecting cavitation events in a soft solid

Garay, Gonzalo - Abraham, Yamil - Cortela Tiboni, Guillermo - Benech, Nicolás - Negreira, Carlos

Resumen:

The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.

Detalles Bibliográficos
2024
Solid modeling
Transducers
Ultrasonic imaging
Correlation
Phantoms
Medical treatment
Solids
Cavitation detection
HIFU
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/48670
Acceso abierto
Licencia Creative Commons Atribución (CC - By 4.0)
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author Garay, Gonzalo
author2 Abraham, Yamil
Cortela Tiboni, Guillermo
Benech, Nicolás
Negreira, Carlos
author2_role author
author
author
author
author_facet Garay, Gonzalo
Abraham, Yamil
Cortela Tiboni, Guillermo
Benech, Nicolás
Negreira, Carlos
author_role author
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http://localhost:8080/xmlui/bitstream/20.500.12008/48670/1/10.1109-LAUS60931.2024.10552982.pdf
collection COLIBRI
dc.contributor.filiacion.none.fl_str_mv Garay Gonzalo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.
Abraham Yamil, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.
Cortela Tiboni Guillermo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.
Benech Nicolás, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.
Negreira Carlos, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.
dc.creator.none.fl_str_mv Garay, Gonzalo
Abraham, Yamil
Cortela Tiboni, Guillermo
Benech, Nicolás
Negreira, Carlos
dc.date.accessioned.none.fl_str_mv 2025-03-13T15:12:58Z
dc.date.available.none.fl_str_mv 2025-03-13T15:12:58Z
dc.date.issued.none.fl_str_mv 2024
dc.description.abstract.none.fl_txt_mv The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.
dc.format.extent.es.fl_str_mv 4 h
dc.format.mimetype.es.fl_str_mv application/pdf
dc.identifier.citation.es.fl_str_mv Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41
dc.identifier.doi.none.fl_str_mv 10.1007/978-3-031-49407-9_41
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12008/48670
dc.language.iso.none.fl_str_mv en
eng
dc.publisher.es.fl_str_mv IEEE
dc.relation.none.fl_str_mv IEEE UFFC Latin America Ultrasonics Symposium, 8-10 May, 2024.
dc.rights.license.none.fl_str_mv Licencia Creative Commons Atribución (CC - By 4.0)
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.source.none.fl_str_mv reponame:COLIBRI
instname:Universidad de la República
instacron:Universidad de la República
dc.subject.es.fl_str_mv Solid modeling
Transducers
Ultrasonic imaging
Correlation
Phantoms
Medical treatment
Solids
Cavitation detection
HIFU
dc.title.none.fl_str_mv Experimental study on the probability of inducing and detecting cavitation events in a soft solid
dc.type.es.fl_str_mv Artículo
dc.type.none.fl_str_mv info:eu-repo/semantics/article
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
description The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.
eu_rights_str_mv openAccess
format article
id COLIBRI_c12a90c9cadecffecdf8c90fc60185f1
identifier_str_mv Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41
10.1007/978-3-031-49407-9_41
instacron_str Universidad de la República
institution Universidad de la República
instname_str Universidad de la República
language eng
language_invalid_str_mv en
network_acronym_str COLIBRI
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oai_identifier_str oai:colibri.udelar.edu.uy:20.500.12008/48670
publishDate 2024
reponame_str COLIBRI
repository.mail.fl_str_mv karina.camps@seciu.edu.uy
repository.name.fl_str_mv COLIBRI - Universidad de la República
repository_id_str 4771
rights_invalid_str_mv Licencia Creative Commons Atribución (CC - By 4.0)
spelling Garay Gonzalo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Abraham Yamil, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Cortela Tiboni Guillermo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Benech Nicolás, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Negreira Carlos, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.2025-03-13T15:12:58Z2025-03-13T15:12:58Z2024Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41https://hdl.handle.net/20.500.12008/4867010.1007/978-3-031-49407-9_41The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.Submitted by Pintos Natalia (nataliapintosmvd@gmail.com) on 2025-03-13T11:35:59Z No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5)Approved for entry into archive by Faget Cecilia (lfaget@fcien.edu.uy) on 2025-03-13T11:38:11Z (GMT) No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2025-03-13T15:12:58Z (GMT). No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5) Previous issue date: 20244 happlication/pdfenengIEEEIEEE UFFC Latin America Ultrasonics Symposium, 8-10 May, 2024.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. 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- Universidad de la Repúblicafalse
spellingShingle Experimental study on the probability of inducing and detecting cavitation events in a soft solid
Garay, Gonzalo
Solid modeling
Transducers
Ultrasonic imaging
Correlation
Phantoms
Medical treatment
Solids
Cavitation detection
HIFU
status_str publishedVersion
title Experimental study on the probability of inducing and detecting cavitation events in a soft solid
title_full Experimental study on the probability of inducing and detecting cavitation events in a soft solid
title_fullStr Experimental study on the probability of inducing and detecting cavitation events in a soft solid
title_full_unstemmed Experimental study on the probability of inducing and detecting cavitation events in a soft solid
title_short Experimental study on the probability of inducing and detecting cavitation events in a soft solid
title_sort Experimental study on the probability of inducing and detecting cavitation events in a soft solid
topic Solid modeling
Transducers
Ultrasonic imaging
Correlation
Phantoms
Medical treatment
Solids
Cavitation detection
HIFU
url https://hdl.handle.net/20.500.12008/48670