Experimental study on the probability of inducing and detecting cavitation events in a soft solid
Resumen:
The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.
| 2024 | |
|
Solid modeling Transducers Ultrasonic imaging Correlation Phantoms Medical treatment Solids Cavitation detection HIFU |
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| Inglés | |
| Universidad de la República | |
| COLIBRI | |
| https://hdl.handle.net/20.500.12008/48670 | |
| Acceso abierto | |
| Licencia Creative Commons Atribución (CC - By 4.0) |
| _version_ | 1875693305061179392 |
|---|---|
| author | Garay, Gonzalo |
| author2 | Abraham, Yamil Cortela Tiboni, Guillermo Benech, Nicolás Negreira, Carlos |
| author2_role | author author author author |
| author_facet | Garay, Gonzalo Abraham, Yamil Cortela Tiboni, Guillermo Benech, Nicolás Negreira, Carlos |
| author_role | author |
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| collection | COLIBRI |
| dc.contributor.filiacion.none.fl_str_mv | Garay Gonzalo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. Abraham Yamil, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. Cortela Tiboni Guillermo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. Benech Nicolás, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. Negreira Carlos, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. |
| dc.creator.none.fl_str_mv | Garay, Gonzalo Abraham, Yamil Cortela Tiboni, Guillermo Benech, Nicolás Negreira, Carlos |
| dc.date.accessioned.none.fl_str_mv | 2025-03-13T15:12:58Z |
| dc.date.available.none.fl_str_mv | 2025-03-13T15:12:58Z |
| dc.date.issued.none.fl_str_mv | 2024 |
| dc.description.abstract.none.fl_txt_mv | The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment. |
| dc.format.extent.es.fl_str_mv | 4 h |
| dc.format.mimetype.es.fl_str_mv | application/pdf |
| dc.identifier.citation.es.fl_str_mv | Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41 |
| dc.identifier.doi.none.fl_str_mv | 10.1007/978-3-031-49407-9_41 |
| dc.identifier.uri.none.fl_str_mv | https://hdl.handle.net/20.500.12008/48670 |
| dc.language.iso.none.fl_str_mv | en eng |
| dc.publisher.es.fl_str_mv | IEEE |
| dc.relation.none.fl_str_mv | IEEE UFFC Latin America Ultrasonics Symposium, 8-10 May, 2024. |
| dc.rights.license.none.fl_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.es.fl_str_mv | Solid modeling Transducers Ultrasonic imaging Correlation Phantoms Medical treatment Solids Cavitation detection HIFU |
| dc.title.none.fl_str_mv | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| dc.type.es.fl_str_mv | Artículo |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.version.none.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | COLIBRI_c12a90c9cadecffecdf8c90fc60185f1 |
| identifier_str_mv | Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41 10.1007/978-3-031-49407-9_41 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | COLIBRI |
| network_name_str | COLIBRI |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/48670 |
| publishDate | 2024 |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | karina.camps@seciu.edu.uy |
| repository.name.fl_str_mv | COLIBRI - Universidad de la República |
| repository_id_str | 4771 |
| rights_invalid_str_mv | Licencia Creative Commons Atribución (CC - By 4.0) |
| spelling | Garay Gonzalo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Abraham Yamil, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Cortela Tiboni Guillermo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Benech Nicolás, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.Negreira Carlos, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.2025-03-13T15:12:58Z2025-03-13T15:12:58Z2024Garay, G, Abraham, Y, Cortela Tiboni, G, [y otros autores]. "Experimental study on the probability of inducing and detecting cavitation events in a soft solid". IEEE UFFC Latin America Ultrasonics Symposium. [en línea] 8-10 May, 2024. 4 h. DOI: 10.1007/978-3-031-49407-9_41https://hdl.handle.net/20.500.12008/4867010.1007/978-3-031-49407-9_41The interaction between an intense ultrasonic field and a soft solid can generate bubbles that expand and collapse, known as acoustic cavitation. Understanding this phenomenon is crucial in controlling the formation of bubbles in specific brain areas during transcranial ultrasound therapies. To achieve this control, establishing an acoustic intensity threshold, be-yond which cavitation is highly probable, becomes essential. As cavitation behavior can vary under identical experimental conditions, considering the probability of its occurrence becomes a crucial variable. This study introduces a passive detection system designed to identify acoustic cavitation, presenting the results of its implementation for a probabilistic analysis of cavitation phenomena. The setup comprises a high-power flat transducer operating at a frequency of 0.94 MHz, generating an acoustic field that traverses an agar-agar phantom. A secondary transducer, purpose-built for cavitation detection, captures the acoustic wave emitted by the phantom. The detection method involves analyzing the wave spectrum to identify the specific acoustic signature of bubbles: a subharmonic spectral component precisely at half the operating frequency. By conducting multiple iterations of the experiment, we determine how often cavitation is detected, thereby empirically establishing the likelihood of this phenomenon occurring. The results illustrate the correlation between the likelihood of cavitation occurrence and the maximum intensity of the applied acoustic field on the phantom. To elucidate the relationship between these variables, we introduce a model derived from calculating the effective volume where the acoustic field exceeds a threshold intensity value. This model aptly describes the experimental outcomes. Future work will extend this analysis to a transcranial HIFU experiment.Submitted by Pintos Natalia (nataliapintosmvd@gmail.com) on 2025-03-13T11:35:59Z No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5)Approved for entry into archive by Faget Cecilia (lfaget@fcien.edu.uy) on 2025-03-13T11:38:11Z (GMT) No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2025-03-13T15:12:58Z (GMT). No. of bitstreams: 2 license_rdf: 24942 bytes, checksum: 58cb336ce230a47d2f88ad02838a665f (MD5) 10.1109-LAUS60931.2024.10552982.pdf: 631755 bytes, checksum: 4542b28d525bf376d736095bede0efa2 (MD5) Previous issue date: 20244 happlication/pdfenengIEEEIEEE UFFC Latin America Ultrasonics Symposium, 8-10 May, 2024.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución (CC - By 4.0)Solid modelingTransducersUltrasonic imagingCorrelationPhantomsMedical treatmentSolidsCavitation detectionHIFUExperimental study on the probability of inducing and detecting cavitation events in a soft solidArtículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaGaray, GonzaloAbraham, YamilCortela Tiboni, GuillermoBenech, NicolásNegreira, CarlosLICENSElicense.txtlicense.txttext/plain; charset=utf-84267http://localhost:8080/xmlui/bitstream/20.500.12008/48670/5/license.txt6429389a7df7277b72b7924fdc7d47a9MD55CC-LICENSElicense_urllicense_urltext/plain; charset=utf-844http://localhost:8080/xmlui/bitstream/20.500.12008/48670/2/license_urla0ebbeafb9d2ec7cbb19d7137ebc392cMD52license_textlicense_texttext/html; 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- Universidad de la Repúblicafalse |
| spellingShingle | Experimental study on the probability of inducing and detecting cavitation events in a soft solid Garay, Gonzalo Solid modeling Transducers Ultrasonic imaging Correlation Phantoms Medical treatment Solids Cavitation detection HIFU |
| status_str | publishedVersion |
| title | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| title_full | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| title_fullStr | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| title_full_unstemmed | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| title_short | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| title_sort | Experimental study on the probability of inducing and detecting cavitation events in a soft solid |
| topic | Solid modeling Transducers Ultrasonic imaging Correlation Phantoms Medical treatment Solids Cavitation detection HIFU |
| url | https://hdl.handle.net/20.500.12008/48670 |