A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma

Bologna-Molina, Ronell - Salazar Rodríguez, Sirced - Bedoya Borella, Ana María - Carreón Burciaga, Ramón Gil - Tapia Repetto, Gabriel - Molina Frechero, Nelly

Resumen:

Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma.This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.


Detalles Bibliográficos
2013
TUMORES ODONTOGENICOS
ODONTOMA
AMELOBLASTOMA
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/31511
Acceso abierto
Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)
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author Bologna-Molina, Ronell
author2 Salazar Rodríguez, Sirced
Bedoya Borella, Ana María
Carreón Burciaga, Ramón Gil
Tapia Repetto, Gabriel
Molina Frechero, Nelly
author2_role author
author
author
author
author
author_facet Bologna-Molina, Ronell
Salazar Rodríguez, Sirced
Bedoya Borella, Ana María
Carreón Burciaga, Ramón Gil
Tapia Repetto, Gabriel
Molina Frechero, Nelly
author_role author
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collection COLIBRI
dc.contributor.filiacion.none.fl_str_mv Bologna Molina Ronell, Oral Pathology, Research Department, School of Dentistry, Universidad Juárez del Estado de Durango, 2School ofDentistry,Universidad de la República Montevideo, Uruguay
Salazar Rodríguez Sirced, Pathology Department, Instituto Nacional de Oncología y Radiobiología Havana, Cuba
Bedoya Borella Ana María, Biology Department, CBC, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina
Carreón Burciaga Ramón Gil , Oral Pathology, Research Department, School of Dentistry, Universidad Juárez del Estado de Durango
Tapia Repetto Gabriel, School of Dentistry,Universidad de la República (UDELAR), Montevideo, Uruguay
Molina Frechero Nelly, Health Care Department, Universidad Autónoma Metropolitana, Xochimilco, Mexico City,DF, Mexico
dc.creator.none.fl_str_mv Bologna-Molina, Ronell
Salazar Rodríguez, Sirced
Bedoya Borella, Ana María
Carreón Burciaga, Ramón Gil
Tapia Repetto, Gabriel
Molina Frechero, Nelly
dc.date.accessioned.none.fl_str_mv 2022-05-09T12:27:10Z
dc.date.available.none.fl_str_mv 2022-05-09T12:27:10Z
dc.date.issued.none.fl_str_mv 2013
dc.description.abstract.none.fl_txt_mv Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma.This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.
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dc.identifier.citation.es.fl_str_mv Bologna-Molina, R, Salazar Rodríguez, S, Bedoya Borella, A. y otros . "A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma"Case Reports in Pathology Volumen 2013. [en línea] 2013. doi.org/10.1155/2013/604560
dc.identifier.doi.none.fl_str_mv doi.org/10.1155/2013/604560
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12008/31511
dc.language.iso.none.fl_str_mv en
eng
dc.relation.ispartof.es.fl_str_mv Case Reports in Pathology Volumen 2013.
dc.rights.license.none.fl_str_mv Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.source.none.fl_str_mv reponame:COLIBRI
instname:Universidad de la República
instacron:Universidad de la República
dc.subject.other.es.fl_str_mv TUMORES ODONTOGENICOS
ODONTOMA
AMELOBLASTOMA
dc.title.none.fl_str_mv A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
dc.type.es.fl_str_mv Artículo
dc.type.none.fl_str_mv info:eu-repo/semantics/article
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
description Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma.This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.
eu_rights_str_mv openAccess
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identifier_str_mv Bologna-Molina, R, Salazar Rodríguez, S, Bedoya Borella, A. y otros . "A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma"Case Reports in Pathology Volumen 2013. [en línea] 2013. doi.org/10.1155/2013/604560
doi.org/10.1155/2013/604560
instacron_str Universidad de la República
institution Universidad de la República
instname_str Universidad de la República
language eng
language_invalid_str_mv en
network_acronym_str COLIBRI
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publishDate 2013
reponame_str COLIBRI
repository.mail.fl_str_mv mabel.seroubian@seciu.edu.uy
repository.name.fl_str_mv COLIBRI - Universidad de la República
repository_id_str 4771
rights_invalid_str_mv Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)
spelling Bologna Molina Ronell, Oral Pathology, Research Department, School of Dentistry, Universidad Juárez del Estado de Durango, 2School ofDentistry,Universidad de la República Montevideo, UruguaySalazar Rodríguez Sirced, Pathology Department, Instituto Nacional de Oncología y Radiobiología Havana, CubaBedoya Borella Ana María, Biology Department, CBC, Universidad de Buenos Aires (UBA), Buenos Aires, ArgentinaCarreón Burciaga Ramón Gil , Oral Pathology, Research Department, School of Dentistry, Universidad Juárez del Estado de DurangoTapia Repetto Gabriel, School of Dentistry,Universidad de la República (UDELAR), Montevideo, UruguayMolina Frechero Nelly, Health Care Department, Universidad Autónoma Metropolitana, Xochimilco, Mexico City,DF, Mexico2022-05-09T12:27:10Z2022-05-09T12:27:10Z2013Bologna-Molina, R, Salazar Rodríguez, S, Bedoya Borella, A. y otros . "A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma"Case Reports in Pathology Volumen 2013. [en línea] 2013. doi.org/10.1155/2013/604560https://hdl.handle.net/20.500.12008/31511doi.org/10.1155/2013/604560Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma.This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.Submitted by Pérez Verónica (verosil22@gmail.com) on 2022-05-09T12:26:18Z No. of bitstreams: 2 license_rdf: 21687 bytes, checksum: 749156fd3854beb422ddf543c77fb5b1 (MD5) A histopathological and immunohistochemical analysis of ameloblastic fibrodentinoma.pdf: 7974407 bytes, checksum: 88aa265b5df9ac625471660e29583ac9 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2022-05-09T12:27:10Z (GMT). No. of bitstreams: 2 license_rdf: 21687 bytes, checksum: 749156fd3854beb422ddf543c77fb5b1 (MD5) A histopathological and immunohistochemical analysis of ameloblastic fibrodentinoma.pdf: 7974407 bytes, checksum: 88aa265b5df9ac625471660e29583ac9 (MD5) Previous issue date: 2013application/pdfenengCase Reports in Pathology Volumen 2013.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)TUMORES ODONTOGENICOSODONTOMAAMELOBLASTOMAA Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinomaArtículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaBologna-Molina, RonellSalazar Rodríguez, SircedBedoya Borella, Ana MaríaCarreón Burciaga, Ramón GilTapia Repetto, GabrielMolina Frechero, NellyLICENSElicense.txtlicense.txttext/plain; charset=utf-84267http://localhost:8080/xmlui/bitstream/20.500.12008/31511/5/license.txt6429389a7df7277b72b7924fdc7d47a9MD55CC-LICENSElicense_urllicense_urltext/plain; charset=utf-847http://localhost:8080/xmlui/bitstream/20.500.12008/31511/2/license_url966d4a1cc97b2c4389b5142dd97d3c7fMD52license_textlicense_texttext/html; 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- Universidad de la Repúblicafalse
spellingShingle A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
Bologna-Molina, Ronell
TUMORES ODONTOGENICOS
ODONTOMA
AMELOBLASTOMA
status_str publishedVersion
title A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
title_full A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
title_fullStr A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
title_full_unstemmed A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
title_short A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
title_sort A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
topic TUMORES ODONTOGENICOS
ODONTOMA
AMELOBLASTOMA
url https://hdl.handle.net/20.500.12008/31511