Epithelial fluid transport is due to electro-osmosis (80%), plus osmosis (20%)

Fischbarg, Jorge - Hernández Garrido, Julio Andrés - Rubashkin, Andrey A. - Iserovich, Pavel - Cacace, Veronica I. - Kusnier, Carlos F.

Resumen:

Epithelial fluid transport, an important physiological process shrouded in a long-standing enigma, may finally be moving closer to a solution. We propose that, for the corneal endothelium, relative proportions for the driving forces for fluid transport are 80% of paracellular electro-osmosis, and 20% classical transcellular osmosis. These operate in a cyclical process with a period of 9.2 s, which is dictated by the decrease and exhaustion of cellular Na?. Paracellular electro-osmosis is sketched here, and partially discussed as much as the subject still allows; transcellular osmosis is presented at length.


Detalles Bibliográficos
2017
Fluid transport
Electro-osmosis
Osmosis
Inglés
Universidad de la República
COLIBRI
https://hdl.handle.net/20.500.12008/35113
Acceso abierto
Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)

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