This report provides an overview of the program, discussions and outcomes of Dagstuhl Seminar 15022 “Quality of Experience: From Assessment to Application”, which took place from 4– 7 January 2015 at Schloss Dagstuhl – Leibniz Center for Informatics. The seminar and the challenges that were addressed have their roots in the earlier Dagstuhl Seminars 09192 “From Quality of Service to Quality of Experience” and 12181 “Quality of Experience: From User Perception to Instrumental Metrics”. The main goal of the seminar was to strengthen and go beyond the current understanding on Quality of Experience (QoE) and its assessment, in order to start tackling the logical yet highly challenging next steps: to move from assessment to application and to translate insights on QoE and knowledge from this research field into forms of economic and/or societal value. This report contains the personal statements and main challenges brought forward by the participants, who were on the fly clustered into six main discussion topics. We here report on the discussions and outcomes from the group work, organized around these bottom-up generated topics: “QoE theory and modeling”, “QoE methodologies”, “User factors and QoE”, “QoE management”, “Monetization of QoE” and “QoE in new domains”.