Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective.
Resumen:
This paper presents a comprehensive review of state-of-the-art, commercially available neurostimulators. We analyse key design parameters and performance metrics of 45 implantable medical devices across six neural target categories: deep brain, vagus nerve, spinal cord, phrenic nerve, sacral nerve and hypoglossal nerve. We then benchmark these alongside modern cardiac pacemaker devices that represent a more established market. This work studies trends in device size, electrode number, battery technology (i.e., primary and secondary use and chemistry), power consumption and longevity. This information is analysed to show the course of design decisions adopted by industry and identifying opportunity for further innovation. We identify fundamental limits in power consumption, longevity and size as well as the interdependencies and trade-offs. We propose a figure of merit to quantify volumetric efficiency within specific therapeutic targets, battery technologies/capacities, charging capabilities and electrode count. Finally, we compare commercially available implantable medical devices with recently developed systems in the research community. We envisage this analysis to aid circuit and system designers in system optimisation and identifying innovation opportunities, particularly those related to low power circuit design techniques.
2023 | |
CSIC - Universidad de la República. | |
Batteries Pain Diseases Medical treatment Sleep apnea Medical devices Sensors Neurostimulators Neuromodulation Implantable medical devices Neural interface Energy efficiency Miniaturisation Batt |
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Inglés | |
Universidad de la República | |
COLIBRI | |
https://ieeexplore.ieee.org/document/9984934
https://hdl.handle.net/20.500.12008/37218 |
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Acceso abierto | |
Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
_version_ | 1807522932840202240 |
---|---|
author | Martínez Bentancor, Santiago |
author2 | Veirano Núñez, Francisco Constandinou, Timothy G. Silveira, Fernando |
author2_role | author author author |
author_facet | Martínez Bentancor, Santiago Veirano Núñez, Francisco Constandinou, Timothy G. Silveira, Fernando |
author_role | author |
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collection | COLIBRI |
dc.contributor.filiacion.none.fl_str_mv | Martínez Bentancor Santiago, Universidad de la República (Uruguay). Facultad de Ingeniería. Veirano Núñez Francisco, Universidad de la República (Uruguay). Facultad de Ingeniería. Constandinou Timothy G., Imperial College London, UK Silveira Fernando, Universidad de la República (Uruguay). Facultad de Ingeniería. |
dc.creator.none.fl_str_mv | Martínez Bentancor, Santiago Veirano Núñez, Francisco Constandinou, Timothy G. Silveira, Fernando |
dc.date.accessioned.none.fl_str_mv | 2023-05-24T13:39:40Z |
dc.date.available.none.fl_str_mv | 2023-05-24T13:39:40Z |
dc.date.issued.none.fl_str_mv | 2023 |
dc.description.abstract.none.fl_txt_mv | This paper presents a comprehensive review of state-of-the-art, commercially available neurostimulators. We analyse key design parameters and performance metrics of 45 implantable medical devices across six neural target categories: deep brain, vagus nerve, spinal cord, phrenic nerve, sacral nerve and hypoglossal nerve. We then benchmark these alongside modern cardiac pacemaker devices that represent a more established market. This work studies trends in device size, electrode number, battery technology (i.e., primary and secondary use and chemistry), power consumption and longevity. This information is analysed to show the course of design decisions adopted by industry and identifying opportunity for further innovation. We identify fundamental limits in power consumption, longevity and size as well as the interdependencies and trade-offs. We propose a figure of merit to quantify volumetric efficiency within specific therapeutic targets, battery technologies/capacities, charging capabilities and electrode count. Finally, we compare commercially available implantable medical devices with recently developed systems in the research community. We envisage this analysis to aid circuit and system designers in system optimisation and identifying innovation opportunities, particularly those related to low power circuit design techniques. |
dc.description.es.fl_txt_mv | Publicado en IEEE Transactions on Biomedical Circuits and Systems, vol. 17, no 1, feb 2023, pp 2-20 |
dc.description.sponsorship.none.fl_txt_mv | CSIC - Universidad de la República. |
dc.format.extent.es.fl_str_mv | 19 p. |
dc.format.mimetype.es.fl_str_mv | application/pdf |
dc.identifier.citation.es.fl_str_mv | Martínez Bentancor, S., Veirano Núñez, F., Constandinou, T. y otros. "Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective" [Preprint]. Publicado en: IEEE Transactions on Biomedical Circuits and Systems. 2023, vol. 17, no 1, pp 2-20. DOI: 10.1109/TBCAS.2022.3228895 |
dc.identifier.issn.none.fl_str_mv | 1932-4545 |
dc.identifier.uri.none.fl_str_mv | https://ieeexplore.ieee.org/document/9984934 https://hdl.handle.net/20.500.12008/37218 |
dc.language.iso.none.fl_str_mv | en eng |
dc.rights.license.none.fl_str_mv | Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
dc.subject.es.fl_str_mv | Batteries Pain Diseases Medical treatment Sleep apnea Medical devices Sensors Neurostimulators Neuromodulation Implantable medical devices Neural interface Energy efficiency Miniaturisation Batt |
dc.title.none.fl_str_mv | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
dc.type.es.fl_str_mv | Preprint |
dc.type.none.fl_str_mv | info:eu-repo/semantics/preprint |
dc.type.version.none.fl_str_mv | info:eu-repo/semantics/submittedVersion |
description | Publicado en IEEE Transactions on Biomedical Circuits and Systems, vol. 17, no 1, feb 2023, pp 2-20 |
eu_rights_str_mv | openAccess |
format | preprint |
id | COLIBRI_17e27a1ca58894e9dd52dc9d04450284 |
identifier_str_mv | Martínez Bentancor, S., Veirano Núñez, F., Constandinou, T. y otros. "Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective" [Preprint]. Publicado en: IEEE Transactions on Biomedical Circuits and Systems. 2023, vol. 17, no 1, pp 2-20. DOI: 10.1109/TBCAS.2022.3228895 1932-4545 |
instacron_str | Universidad de la República |
institution | Universidad de la República |
instname_str | Universidad de la República |
language | eng |
language_invalid_str_mv | en |
network_acronym_str | COLIBRI |
network_name_str | COLIBRI |
oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/37218 |
publishDate | 2023 |
reponame_str | COLIBRI |
repository.mail.fl_str_mv | mabel.seroubian@seciu.edu.uy |
repository.name.fl_str_mv | COLIBRI - Universidad de la República |
repository_id_str | 4771 |
rights_invalid_str_mv | Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
spelling | Martínez Bentancor Santiago, Universidad de la República (Uruguay). Facultad de Ingeniería.Veirano Núñez Francisco, Universidad de la República (Uruguay). Facultad de Ingeniería.Constandinou Timothy G., Imperial College London, UKSilveira Fernando, Universidad de la República (Uruguay). Facultad de Ingeniería.2023-05-24T13:39:40Z2023-05-24T13:39:40Z2023Martínez Bentancor, S., Veirano Núñez, F., Constandinou, T. y otros. "Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective" [Preprint]. Publicado en: IEEE Transactions on Biomedical Circuits and Systems. 2023, vol. 17, no 1, pp 2-20. DOI: 10.1109/TBCAS.2022.32288951932-4545https://ieeexplore.ieee.org/document/9984934https://hdl.handle.net/20.500.12008/37218Publicado en IEEE Transactions on Biomedical Circuits and Systems, vol. 17, no 1, feb 2023, pp 2-20This paper presents a comprehensive review of state-of-the-art, commercially available neurostimulators. We analyse key design parameters and performance metrics of 45 implantable medical devices across six neural target categories: deep brain, vagus nerve, spinal cord, phrenic nerve, sacral nerve and hypoglossal nerve. We then benchmark these alongside modern cardiac pacemaker devices that represent a more established market. This work studies trends in device size, electrode number, battery technology (i.e., primary and secondary use and chemistry), power consumption and longevity. This information is analysed to show the course of design decisions adopted by industry and identifying opportunity for further innovation. We identify fundamental limits in power consumption, longevity and size as well as the interdependencies and trade-offs. We propose a figure of merit to quantify volumetric efficiency within specific therapeutic targets, battery technologies/capacities, charging capabilities and electrode count. Finally, we compare commercially available implantable medical devices with recently developed systems in the research community. We envisage this analysis to aid circuit and system designers in system optimisation and identifying innovation opportunities, particularly those related to low power circuit design techniques.Submitted by Ribeiro Jorge (jribeiro@fing.edu.uy) on 2023-05-20T00:36:01Z No. of bitstreams: 2 license_rdf: 23149 bytes, checksum: 1996b8461bc290aef6a27d78c67b6b52 (MD5) MVCS23.pdf: 12537968 bytes, checksum: 0a2d04d4c578e899492a4744bffd0dd8 (MD5)Approved for entry into archive by Berón Cecilia (cberon@fing.edu.uy) on 2023-05-23T18:37:24Z (GMT) No. of bitstreams: 2 license_rdf: 23149 bytes, checksum: 1996b8461bc290aef6a27d78c67b6b52 (MD5) MVCS23.pdf: 12537968 bytes, checksum: 0a2d04d4c578e899492a4744bffd0dd8 (MD5)Made available in DSpace by Luna Fabiana (fabiana.luna@seciu.edu.uy) on 2023-05-24T13:39:40Z (GMT). No. of bitstreams: 2 license_rdf: 23149 bytes, checksum: 1996b8461bc290aef6a27d78c67b6b52 (MD5) MVCS23.pdf: 12537968 bytes, checksum: 0a2d04d4c578e899492a4744bffd0dd8 (MD5) Previous issue date: 2023CSIC - Universidad de la República.19 p.application/pdfenengLas obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)BatteriesPainDiseasesMedical treatmentSleep apneaMedical devicesSensorsNeurostimulatorsNeuromodulationImplantable medical devicesNeural interfaceEnergy efficiencyMiniaturisationBattTrends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective.Preprintinfo:eu-repo/semantics/preprintinfo:eu-repo/semantics/submittedVersionreponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaMartínez Bentancor, SantiagoVeirano Núñez, FranciscoConstandinou, Timothy G.Silveira, FernandoLICENSElicense.txtlicense.txttext/plain; charset=utf-84267http://localhost:8080/xmlui/bitstream/20.500.12008/37218/5/license.txt6429389a7df7277b72b7924fdc7d47a9MD55CC-LICENSElicense_urllicense_urltext/plain; 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- Universidad de la Repúblicafalse |
spellingShingle | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. Martínez Bentancor, Santiago Batteries Pain Diseases Medical treatment Sleep apnea Medical devices Sensors Neurostimulators Neuromodulation Implantable medical devices Neural interface Energy efficiency Miniaturisation Batt |
status_str | submittedVersion |
title | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
title_full | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
title_fullStr | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
title_full_unstemmed | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
title_short | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
title_sort | Trends in volumetric-energy efficiency of implantable neurostimulators : A review from a circuits and systems perspective. |
topic | Batteries Pain Diseases Medical treatment Sleep apnea Medical devices Sensors Neurostimulators Neuromodulation Implantable medical devices Neural interface Energy efficiency Miniaturisation Batt |
url | https://ieeexplore.ieee.org/document/9984934 https://hdl.handle.net/20.500.12008/37218 |